WFS1

Gene Symbol WFS1
Entrez Gene 7466
Alt Symbol CTRCT41, WFRS, WFS, WFSL
Species Human
Gene Type protein-coding
Description Wolfram syndrome 1 (wolframin)
Other Description wolframin
Swissprots B2R797 Q9UNW6 Q8N6I3 O76024 D3DVT1
Accessions AGX00084 AKA98155 EAW82396 EAW82397 EAW82398 O76024 AF084481 AAC64943 AK295986 BAG58761 AK312897 BAG35744 BC030130 AAH30130 BC069213 EU176760 ABW03561 Y18064 CAA77022 NM_001145853 NP_001139325 NM_006005 NP_005996
Function Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store. {ECO:0000269|PubMed:16989814}.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity Highly expressed in heart followed by brain, placenta, lung and pancreas. Weakly expressed in liver, kidney and skeletal muscle. Also expressed in islet and beta-cell insulinoma cell line.
Top Pathways Protein processing in endoplasmic reticulum

WFS1 Antibody - 8749 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using WFS1 Antibody.

Wolframin (E-18) - sc-47937 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Wolframin (H-215) - sc-67180 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Wolframin (H-215): sc-67180. Western blot analysis of Wolframin expression in HeLa whole cell lysate.

Wolframin (T-20) - sc-47942 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Wolframin (T-20): sc-47942. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of Islets of Langerhans.

Wolframin (C-18) - sc-47936 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-WFS1 antibody - ab176909 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-WFS1 antibody (ab176909) at 1/500 dilutionLane 1 : Human fetal heart lysateLane 2 : Human fetal muscle lysate

Anti-WFS1 antibody - ab135893 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-WFS1 antibody (ab135893) at 1/500 dilution + Human brain tissue lysate at 30 µg

Anti-WFS1 antibody - Aminoterminal end - ab48169 from Abcam

Prices $394.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab48169 staining WFS1 in HeLa cells by Immunocytochemistry/ Immunofluorescence.Cells were fixed in paraformaldehyde, permeabilized using 0.5% Triton-X, blocked with 3% BSA for 1 hour at 23°C, then incubated with ab48169 at a 1/100 dilution for 1 hour at 23°C. The secondary used was an Alexa-Fluor 488 conjugated goat anti-rabbit polyclonal, used at a 1/2000 dilution.See Abreview

Anti-WFS1 Antibody (aa100-200) - LS-C95284 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-WFS1 Antibody (N-Terminus) - LS-C90493 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-WFS1 Antibody - LS-C314110 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-WFS1 Antibody - LS-C335172 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of mouse brain cell lines, using WFS1 antibody.

Anti-WFS1 Antibody - LS-C192933 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts of mouse brain cell lines, using WFS1 antibody.

Anti-WFS1 Antibody (aa183-232) IHC-plus™ - LS-B10927 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-WFS1 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10927 concentration 5 ug/ml.

Anti-WFS1 Antibody (N-Terminus) IHC-plus™ - LS-B11791 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

WFS1 Antibody - NB100-1918 from Novus Biologicals

Prices $309.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: WFS1 Antibody [NB100-1918] - Analysis of WFS1 in insulinoma cells.

WFS1 Antibody - AF7417 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Sheep
Clonality Polyclonal

WFS1 Antibody - NBP1-84265 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

WFS1 Polyclonal Antibody - bs-11272R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Human Raji cells probed with WFS1 Polyclonal Antibody, unconjugated (bs-11272R) at 1:300 overnight at 4°C followed by a conjugated secondary antibody at 1:10000 for 90 minutes at 37°C.

WFS1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11272R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

WFS1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11272R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

WFS1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11272R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

WFS1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11272R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

WFS1 Polyclonal Antibody, Cy3 Conjugated - bs-11272R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

WFS1 Polyclonal Antibody, Cy5 Conjugated - bs-11272R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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