WFS1

Gene Symbol	WFS1
Entrez Gene	7466
Alt Symbol	CTRCT41, WFRS, WFS, WFSL
Species	Human
Gene Type	protein-coding
Description	Wolfram syndrome 1 (wolframin)
Other Description	wolframin
Swissprots	B2R797 Q9UNW6 Q8N6I3 O76024 D3DVT1
Accessions	AGX00084 AKA98155 EAW82396 EAW82397 EAW82398 O76024 AF084481 AAC64943 AK295986 BAG58761 AK312897 BAG35744 BC030130 AAH30130 BC069213 EU176760 ABW03561 Y18064 CAA77022 NM_001145853 NP_001139325 NM_006005 NP_005996
Function	Participates in the regulation of cellular Ca(2+) homeostasis, at least partly, by modulating the filling state of the endoplasmic reticulum Ca(2+) store. {ECO:0000269|PubMed:16989814}.
Subcellular Location	Endoplasmic reticulum membrane; Multi-pass membrane protein.
Tissue Specificity	Highly expressed in heart followed by brain, placenta, lung and pancreas. Weakly expressed in liver, kidney and skeletal muscle. Also expressed in islet and beta-cell insulinoma cell line.
Top Pathways	Protein processing in endoplasmic reticulum

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

WFS1 Blocking Peptide - abx063425 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

WFS1 fusion protein - ag18826 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

WFS1 fusion protein - ag2114 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Wolfram Syndrome Protein 1 (WFS1) - RPL118Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Wolfram Syndrome Protein 1 (WFS1) - RPL118Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Wolfram Syndrome Protein 1 (WFS1) - RPL118Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Wolfram Syndrome Protein 1 (WFS1) - RPL118Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

WFS1 Blocking Peptide - CBP2231 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

WFS1 Peptide - BS60455P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Wolfram Syndrome Protein 1 (WFS1) - RPL118Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Wolframin / WFS1 (transcript variant 1) - TP302901 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Wolframin / WFS1 (transcript variant 2) - TP327925 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Wolframin (WFS1), Recombinant Protein - MBS1039162 from MyBioSource Category Protein Prices $1,375.00, $1,835.00 Sizes 1 mg (E-Coli), 1 mg (Yeast) Source E Coli or Yeast Species Human

WFS1 Recombinant Protein Antigen - NBP1-84265PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

WFS1 Peptide, Human - M34GP17490H from Creative Peptides Category Peptide Source Synthetic. Species Human

WFS1 fusion protein - Ag25735 from Proteintech Group Category Protein Source E. coli -derived, PET28a Species Human

WFS1 fusion protein - Ag25724 from Proteintech Group Category Protein Source E. coli -derived, PGEX-4T Species Human

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