| Gene Symbol |
SH3RF1
|
| Entrez Gene |
57630
|
| Alt Symbol |
POSH, RNF142, SH3MD2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SH3 domain containing ring finger 1
|
| Other Description |
E3 ubiquitin-protein ligase SH3RF1|SH3 domain-containing RING finger protein 1|SH3 multiple domains 2|SH3 multiple domains protein 2|plenty of SH3 domains|plenty of SH3s|putative E3 ubiquitin-protein ligase SH3RF1|ring finger protein 142
|
| Swissprots |
Q7Z6J0 Q05BT2 Q8IW46 Q9HAM2 Q9P234
|
| Accessions |
EAX04792 EAX04793 EAX04794 Q7Z6J0 AB040927 BAA96018 AK021429 BAB13822 AK025255 AK026726 BC033203 AAH33203 BC041023 AAH41023 BC053671 AAH53671 DA292937 NM_020870 NP_065921
|
| Function |
Plays an essential role in the targeting of HIV-1 Gag to the plasma membrane, this function is dependent on it's RING domain, and hence it's E3 ligase activity.
|
| Subcellular Location |
Cytoplasm, perinuclear region {ECO:0000250}. Cell projection, lamellipodium. Cytoplasm. Golgi apparatus, trans- Golgi network. Note=Colocalizes, with AKT2, in lamellipodia (By similarity). Colocalizes, with HERP1, in trans-Golgi network. {ECO:0000250}.
|