Gene Symbol | SH3RF1 |
---|---|
Entrez Gene | 57630 |
Alt Symbol | POSH, RNF142, SH3MD2 |
Species | Human |
Gene Type | protein-coding |
Description | SH3 domain containing ring finger 1 |
Other Description | E3 ubiquitin-protein ligase SH3RF1|SH3 domain-containing RING finger protein 1|SH3 multiple domains 2|SH3 multiple domains protein 2|plenty of SH3 domains|plenty of SH3s|putative E3 ubiquitin-protein ligase SH3RF1|ring finger protein 142 |
Swissprots | Q7Z6J0 Q05BT2 Q8IW46 Q9HAM2 Q9P234 |
Accessions | EAX04792 EAX04793 EAX04794 Q7Z6J0 AB040927 BAA96018 AK021429 BAB13822 AK025255 AK026726 BC033203 AAH33203 BC041023 AAH41023 BC053671 AAH53671 DA292937 NM_020870 NP_065921 |
Function | Plays an essential role in the targeting of HIV-1 Gag to the plasma membrane, this function is dependent on it's RING domain, and hence it's E3 ligase activity. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000250}. Cell projection, lamellipodium. Cytoplasm. Golgi apparatus, trans- Golgi network. Note=Colocalizes, with AKT2, in lamellipodia (By similarity). Colocalizes, with HERP1, in trans-Golgi network. {ECO:0000250}. |
POSH CRISPR/Cas9 KO Plasmid (h) - sc-405556 from Santa Cruz Biotechnology
|
||||||||
POSH HDR Plasmid (h) - sc-405556-HDR from Santa Cruz Biotechnology
|
||||||||
POSH Double Nickase Plasmid (h) - sc-405556-NIC from Santa Cruz Biotechnology
|
||||||||
POSH Double Nickase Plasmid (h2) - sc-405556-NIC-2 from Santa Cruz Biotechnology
|
||||||||
POSH CRISPR Activation Plasmid (h) - sc-405556-ACT from Santa Cruz Biotechnology
|
||||||||
POSH CRISPR Activation Plasmid (h2) - sc-405556-ACT-2 from Santa Cruz Biotechnology
|
||||||||
POSH Lentiviral Activation Particles (h) - sc-405556-LAC from Santa Cruz Biotechnology
|
||||||||
POSH Lentiviral Activation Particles (h2) - sc-405556-LAC-2 from Santa Cruz Biotechnology
|
||||||||
POSH siRNA (h) - sc-36293 from Santa Cruz Biotechnology
|
||||||||
POSH shRNA Plasmid (h) - sc-36293-SH from Santa Cruz Biotechnology
|
||||||||
POSH shRNA (h) Lentiviral Particles - sc-36293-V from Santa Cruz Biotechnology
|
||||||||
SH3MD2 RNAi - H00057630-R01 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU133101 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN19278 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19278 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR11325 from Sigma-Aldrich
|
||||||||
SH3RF1 siRNA (Human) - CRJ1594 from Cohesion Biosciences
|
||||||||
SH3RF1 - MBS8238588 from MyBioSource
|
||||||||
shRNA set against Human SH3RF1 (NM_020870.3) - SHH406832 from Creative biogene
|
||||||||
shRNA set against Human SH3RF1(NM_020870.3) - SHR223474 from Creative biogene
|
||||||||
SH3RF1 shRNA Plasmid (Human) - CHJ1594 from Cohesion Biosciences
|
||||||||
SH3RF1 miRNA 3'UTR clone - MiUTR1H-09368 from Creative biogene
|