| Gene Symbol |
STXBP4
|
| Entrez Gene |
252983
|
| Alt Symbol |
Synip
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
syntaxin binding protein 4
|
| Other Description |
STX4-interacting protein|syntaxin 4 interacting protein|syntaxin 4-interacting protein|syntaxin-binding protein 4
|
| Swissprots |
Q8IVZ5 Q6ZWJ1
|
| Accessions |
EAW94545 EAW94546 Q6ZWJ1 AK122865 BAC85511 AK123793 BC041485 AAH41485 BC125116 AAI25117 CA848494 XM_005257187 XP_005257244 XM_006721797 XP_006721860 XM_006721798 XP_006721861 XM_011524581 XP_011522883 XM_011524582 XP_011522884 XM_011524583 XP_011522885 XM_011524584 XP_011522886 XR_934431 NM_178509 NP_848604
|
| Function |
Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}.
|