| Gene Symbol |
VASN
|
| Entrez Gene |
114990
|
| Alt Symbol |
SLITL2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vasorin
|
| Other Description |
protein slit-like 2|slit-like 2
|
| Swissprots |
Q6UXL4 Q6EMK4 Q6UXL5 Q96CX1
|
| Accessions |
EAW85311 Q6EMK4 AY166584 AAO27704 AY358298 AAQ88665 AY358299 AAQ88666 BC013767 AAH13767 BC068575 AAH68575 NM_138440 NP_612449
|
| Function |
May act as an inhibitor of TGF-beta signaling. {ECO:0000269|PubMed:15247411}.
|
| Subcellular Location |
Membrane {ECO:0000305|PubMed:15247411}; Single-pass type I membrane protein {ECO:0000305|PubMed:15247411}. Secreted {ECO:0000269|PubMed:15247411}.
|
| Tissue Specificity |
Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells. {ECO:0000269|PubMed:15247411}.
|