Gene Symbol | VASN |
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Entrez Gene | 114990 |
Alt Symbol | SLITL2 |
Species | Human |
Gene Type | protein-coding |
Description | vasorin |
Other Description | protein slit-like 2|slit-like 2 |
Swissprots | Q6UXL4 Q6EMK4 Q6UXL5 Q96CX1 |
Accessions | EAW85311 Q6EMK4 AY166584 AAO27704 AY358298 AAQ88665 AY358299 AAQ88666 BC013767 AAH13767 BC068575 AAH68575 NM_138440 NP_612449 |
Function | May act as an inhibitor of TGF-beta signaling. {ECO:0000269|PubMed:15247411}. |
Subcellular Location | Membrane {ECO:0000305|PubMed:15247411}; Single-pass type I membrane protein {ECO:0000305|PubMed:15247411}. Secreted {ECO:0000269|PubMed:15247411}. |
Tissue Specificity | Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells. {ECO:0000269|PubMed:15247411}. |
Vasorin CRISPR/Cas9 KO Plasmid (h) - sc-404942 from Santa Cruz Biotechnology
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Vasorin HDR Plasmid (h) - sc-404942-HDR from Santa Cruz Biotechnology
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Vasorin Double Nickase Plasmid (h) - sc-404942-NIC from Santa Cruz Biotechnology
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Vasorin Double Nickase Plasmid (h2) - sc-404942-NIC-2 from Santa Cruz Biotechnology
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Vasorin CRISPR Activation Plasmid (h) - sc-404942-ACT from Santa Cruz Biotechnology
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Vasorin CRISPR Activation Plasmid (h2) - sc-404942-ACT-2 from Santa Cruz Biotechnology
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Vasorin Lentiviral Activation Particles (h) - sc-404942-LAC from Santa Cruz Biotechnology
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Vasorin Lentiviral Activation Particles (h2) - sc-404942-LAC-2 from Santa Cruz Biotechnology
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Vasorin siRNA (h) - sc-61778 from Santa Cruz Biotechnology
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Vasorin shRNA Plasmid (h) - sc-61778-SH from Santa Cruz Biotechnology
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Vasorin shRNA (h) Lentiviral Particles - sc-61778-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU014761 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22644 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22644 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05405 from Sigma-Aldrich
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VASN siRNA (Human) - CRJ4423 from Cohesion Biosciences
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Vasorin/SLIT-like 2 RNAi - H00114990-R01 from Novus Biologicals
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VASN - MBS8210783 from MyBioSource
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shRNA set against Human VASN (NM_138440.2) - SHH442308 from Creative biogene
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Human VASN siRNA - orb274924 from Biorbyt
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VASN shRNA Plasmid (Human) - CHJ4423 from Cohesion Biosciences
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VASN miRNA 3'UTR clone - MiUTR1H-11097 from Creative biogene
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