| Gene Symbol |
ZWINT
|
| Entrez Gene |
11130
|
| Alt Symbol |
HZwint-1, KNTC2AP, SIP30, ZWINT1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ZW10 interacting kinetochore protein
|
| Other Description |
SNAP25 interacting protein of 30 kDa|ZW10 interactor|ZW10 interactor, kinetochore protein|human ZW10 interacting protein-1|zwint-1
|
| Swissprots |
Q0D2I3 A6NNV6 O95229 Q9BWD0
|
| Accessions |
EAW54154 EAW54155 EAW54156 EAW54157 EAW54158 EAW54159 O95229 AF067656 AAC78629 AK093808 BAG52767 AK225509 AK293416 BAG56923 AK298148 BAG60424 BC000411 AAH00411 BC016357 BC020979 AAH20979 BC110399 AAI10400 BG615304 BM724168 JF432678 ADZ15895 XR_428692 NM_001005413 NP_001005413 NM_007057 NP_008988 NM_032997 NP_127490 NM_001005414
|
| Function |
Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase. {ECO:0000269|PubMed:15094189, ECO:0000269|PubMed:15485811, ECO:0000269|PubMed:15824131, ECO:0000269|PubMed:16732327}.
|
| Subcellular Location |
Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase.
|