Gene Symbol | ZWINT |
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Entrez Gene | 11130 |
Alt Symbol | HZwint-1, KNTC2AP, SIP30, ZWINT1 |
Species | Human |
Gene Type | protein-coding |
Description | ZW10 interacting kinetochore protein |
Other Description | SNAP25 interacting protein of 30 kDa|ZW10 interactor|ZW10 interactor, kinetochore protein|human ZW10 interacting protein-1|zwint-1 |
Swissprots | Q0D2I3 A6NNV6 O95229 Q9BWD0 |
Accessions | EAW54154 EAW54155 EAW54156 EAW54157 EAW54158 EAW54159 O95229 AF067656 AAC78629 AK093808 BAG52767 AK225509 AK293416 BAG56923 AK298148 BAG60424 BC000411 AAH00411 BC016357 BC020979 AAH20979 BC110399 AAI10400 BG615304 BM724168 JF432678 ADZ15895 XR_428692 NM_001005413 NP_001005413 NM_007057 NP_008988 NM_032997 NP_127490 NM_001005414 |
Function | Part of the MIS12 complex, which is required for kinetochore formation and spindle checkpoint activity. Required to target ZW10 to the kinetochore at prometaphase. {ECO:0000269|PubMed:15094189, ECO:0000269|PubMed:15485811, ECO:0000269|PubMed:15824131, ECO:0000269|PubMed:16732327}. |
Subcellular Location | Nucleus. Chromosome, centromere, kinetochore. Note=Localizes to kinetochores from late prophase to anaphase. |
ZWINT CRISPR/Cas9 KO Plasmid (h) - sc-405718 from Santa Cruz Biotechnology
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ZWINT HDR Plasmid (h) - sc-405718-HDR from Santa Cruz Biotechnology
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ZWINT Double Nickase Plasmid (h) - sc-405718-NIC from Santa Cruz Biotechnology
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ZWINT Double Nickase Plasmid (h2) - sc-405718-NIC-2 from Santa Cruz Biotechnology
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ZWINT CRISPR Activation Plasmid (h) - sc-405718-ACT from Santa Cruz Biotechnology
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ZWINT CRISPR Activation Plasmid (h2) - sc-405718-ACT-2 from Santa Cruz Biotechnology
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ZWINT Lentiviral Activation Particles (h) - sc-405718-LAC from Santa Cruz Biotechnology
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ZWINT Lentiviral Activation Particles (h2) - sc-405718-LAC-2 from Santa Cruz Biotechnology
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ZWINT siRNA (h) - sc-63263 from Santa Cruz Biotechnology
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ZWINT shRNA Plasmid (h) - sc-63263-SH from Santa Cruz Biotechnology
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ZWINT shRNA (h) Lentiviral Particles - sc-63263-V from Santa Cruz Biotechnology
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ZWINT RNAi - H00011130-R02 from Novus Biologicals
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ZWINT RNAi - H00011130-R01 from Novus Biologicals
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ZWINT RNAi - H00011130-R03 from Novus Biologicals
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MISSION® esiRNA - EHU073921 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23823 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23823 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07503 from Sigma-Aldrich
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ZWINT siRNA (Human) - CRH7614 from Cohesion Biosciences
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ZWINT - MBS8209158 from MyBioSource
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shRNA set against Human ZWINT (NM_007057.3) - SHH456140 from Creative biogene
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shRNA set against Human ZWINT(NM_007057.3) - SHL163686 from Creative biogene
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shRNA set against Human ZWINT(NM_001005413.1) - SHL163722 from Creative biogene
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Human ZWINT siRNA - orb268116 from Biorbyt
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ZWINT shRNA Plasmid (Human) - CHH7614 from Cohesion Biosciences
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