SERBP1

Gene Symbol	SERBP1
Entrez Gene	26135
Alt Symbol	CGI-55, CHD3IP, HABP4L, PAI-RBP1, PAIRBP1
Species	Human
Gene Type	protein-coding
Description	SERPINE1 mRNA binding protein 1
Other Description	PAI-1 mRNA binding protein\|PAI1 RNA-binding protein 1\|SERPINE1 mRNA-binding protein 1\|chromodomain helicase DNA binding protein 3 interacting protein\|plasminogen activator inhibitor 1 RNA binding protein\|plasminogen activator inhibitor 1 RNA-binding protein
Swissprots	Q5VU19 Q9Y4S3 Q9BUM4 Q5VU22 Q8WUH0 Q9Y367 Q8NC51 Q5VU20 Q96SE2 Q9BTY3
Accessions	EAX06489 EAX06490 EAX06491 EAX06492 EAX06493 EAX06494 EAX06495 EAX06496 EAX06497 Q8NC51 AF131807 AF151813 AAD34050 AK074970 BAC11324 AK095960 AK130606 AK222955 BAD96675 AK223138 BAD96858 AK312256 BAG35188 AL080119 CAB45718 AY032853 AAK51130 BC002488 AAH02488 BC003049 AAH03049 BC008045 AAH08045 BC017449 AAH17449 BC019273 AAH19273 BC020555 AAH20555 BC026916 AAH26916 BC036414 BI464676 BX647139 CAH56188 CR457383 CAG33664 EU831446 ACE87133 EU831638 ACE87238 EU831722 ACE86556 EU832650 ACE87741 EU832728 ACE87060 HQ447687 ADQ32172 NM_001018067 NP_001018077 NM_001018068 NP_001018078 NM_001018069 NP_001018079 NM_015640 NP_056455
Function	May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.
Subcellular Location	Cytoplasm {ECO:0000269\|PubMed:12505151}. Nucleus {ECO:0000269\|PubMed:12505151}. Cytoplasm, perinuclear region {ECO:0000269\|PubMed:12505151}. Note=Also found in perinuclear regions.
Tissue Specificity	Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain. {ECO:0000269\|PubMed:12505151}.

PAI-RBP1 (F-8) - sc-376832 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

PAI-RBP1 (F-8): sc-376832. Western blot analysis of PAI-RBP1 expression in Caki-1 (A) and SJRH30 (B) whole cell lysates.

PAI-RBP1 (G-15) - sc-131741 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

PAI-RBP1 (G-15): sc-131741. Western blot analysis of PAI-RBP1 expression in HeLa whole cell lysate.

PAI-RBP1 (N-12) - sc-131742 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

PAI-RBP1 (N-12): sc-131742. Western blot analysis of PAI-RBP1 expression in non-transfected: sc-117752 (A) and mouse PAI-RBP1 transfected: sc-122356 (B) 293T whole cell lysates.

PAI-RBP1 (S-13) - sc-131743 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Goat
Clonality	Polyclonal

PAI-RBP1 (S-13): sc-131743. Western blot analysis of PAI-RBP1 expression in non-transfected: sc-117752 (A) and mouse PAI-RBP1 transfected: sc-122356 (B) 293T whole cell lysates.

PAI-RBP1 (1B9) - sc-100800 from Santa Cruz Biotechnology

Prices	$295.00
Sizes	100 µg/ml
Host	Mouse
Clonality	Monoclonal

PAI-RBP1 (1B9): sc-100800. Immunofluorescence staining of paraformaldehyde-fixed HeLa cells showing cytoplasmic localization.

Anti-SERBP1 antibody - ab57285 from Abcam

Prices	$390.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal

SERBP1 antibody (ab57285) used in immunofluorescence at 10ug/ml on HeLa cells.

Anti-SERBP1 antibody - ab55993 from Abcam

Prices	$384.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SERBP1 antibody [4G2] - ab139347 from Abcam

Prices	$376.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	4G2

All lanes : Anti-SERBP1 antibody [4G2] (ab139347) at 1/2000 dilutionLane 1 : HEK293T cells transfected with pCMV6-ENTRY control cDNA Lane 2 : HEK293T cells transfected with pCMV6-ENTRY SERBP1 cDNALysates/proteins at 5 µg per lane.

Anti-SERBP1 antibody - Aminoterminal end - ab55994 from Abcam

Prices	$370.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-SERBP1 antibody - N-terminal - ab200439 from Abcam

Host	Rabbit
Clonality	Polyclonal

Anti-SERBP1 antibody - N-terminal (ab200439) at 1/1000 dilution + HeLa cell extract

Anti-PAI-RBP1 / SERBP1 Antibody (clone 5G2) - LS-C175446 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	5G2

IHC of paraffin-embedded Carcinoma of Human thyroid tissue using anti-SERBP1 mouse monoclonal antibody.

Anti-PAI-RBP1 / SERBP1 Antibody (N-Terminus) - LS-C47077 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PAI-RBP1 / SERBP1 Antibody (C-Terminus) - LS-C47078 from LifeSpan Bioscience

Prices	$315.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PAI-RBP1 / SERBP1 Antibody (clone 4F8) - LS-C175444 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	4F8

IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-SERBP1 mouse monoclonal antibody.

Anti-PAI-RBP1 / SERBP1 Antibody (clone 4G2) - LS-C175440 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	4G2

IHC of paraffin-embedded Human lymph node tissue using anti-SERBP1 mouse monoclonal antibody.

Anti-PAI-RBP1 / SERBP1 Antibody (clone 2F6) - LS-C175442 from LifeSpan Bioscience

Prices	$350.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	2F6

Anti-PAI-RBP1 / SERBP1 Antibody (aa1-262, clone 1E7) - LS-C337010 from LifeSpan Bioscience

Prices	$325.00
Sizes	100 µl
Host	Mouse
Clonality	Monoclonal
Clone	1E7

IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-SERBP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-PAI-RBP1 / SERBP1 Antibody (aa243-292) - LS-C30469 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Anti-PAI-RBP1 / SERBP1 Antibody - LS-C155334 from LifeSpan Bioscience

Prices	$335.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Sample (30 ug of whole cell lysate) A: HeLa 10% SDS PAGE SERBP1 antibody diluted at 1:1000

Anti-PAI-RBP1 / SERBP1 Antibody (clone 1G5-2D7) - LS-C134056 from LifeSpan Bioscience

Prices	$355.00
Sizes	100 µg
Host	Mouse
Clonality	Monoclonal
Clone	1G5-2D7

Detection limit for recombinant GST tagged SERBP1 is 0.03 ng/ml as a capture antibody.

Anti-PAI-RBP1 / SERBP1 Antibody (aa311-360) - LS-C80312 from LifeSpan Bioscience

Prices	$365.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Heart cell lysate. Antibody concentration: 0.5 ug/ml. Gel concentration: 12%.

Anti-PAI-RBP1 / SERBP1 Antibody (aa1-403, Azide-free) - LS-C328261 from LifeSpan Bioscience

Host	Mouse
Clonality	Monoclonal

Anti-PAI-RBP1 / SERBP1 Antibody - LS-C334495 from LifeSpan Bioscience

Prices	$315.00
Sizes	50 µg
Host	Rabbit
Clonality	Polyclonal

Western blot analysis of extracts of various cell lines, using SERBP1 antibody.

Anti-PAI-RBP1 / SERBP1 Antibody (aa100-150) - LS-C290586 from LifeSpan Bioscience

Prices	$375.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Detection of Human SERBP1 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP; 20% of IP loaded) from 293T cells. Antibodies: Affinity purified rabbit anti-SERBP1 antibody used for IP at 6 ug/mg lysate. SERBP1 was also immunoprecipitated by rabbit anti-SERBP1 antibody BL14099. For blotting immunoprecipitated SERBP1, was used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-SERPINA5 / PCI Antibody (Leu291) - LS-C177387 from LifeSpan Bioscience

Prices	$345.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

IHC of PAI-3 (L291) pAb in paraffin-embedded human liver carcinoma.

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