| Gene Symbol |
SERBP1
|
| Entrez Gene |
26135
|
| Alt Symbol |
CGI-55, CHD3IP, HABP4L, PAI-RBP1, PAIRBP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
SERPINE1 mRNA binding protein 1
|
| Other Description |
PAI-1 mRNA binding protein|PAI1 RNA-binding protein 1|SERPINE1 mRNA-binding protein 1|chromodomain helicase DNA binding protein 3 interacting protein|plasminogen activator inhibitor 1 RNA binding protein|plasminogen activator inhibitor 1 RNA-binding protein
|
| Swissprots |
Q5VU19 Q9Y4S3 Q9BUM4 Q5VU22 Q8WUH0 Q9Y367 Q8NC51 Q5VU20 Q96SE2 Q9BTY3
|
| Accessions |
EAX06489 EAX06490 EAX06491 EAX06492 EAX06493 EAX06494 EAX06495 EAX06496 EAX06497 Q8NC51 AF131807 AF151813 AAD34050 AK074970 BAC11324 AK095960 AK130606 AK222955 BAD96675 AK223138 BAD96858 AK312256 BAG35188 AL080119 CAB45718 AY032853 AAK51130 BC002488 AAH02488 BC003049 AAH03049 BC008045 AAH08045 BC017449 AAH17449 BC019273 AAH19273 BC020555 AAH20555 BC026916 AAH26916 BC036414 BI464676 BX647139 CAH56188 CR457383 CAG33664 EU831446 ACE87133 EU831638 ACE87238 EU831722 ACE86556 EU832650 ACE87741 EU832728 ACE87060 HQ447687 ADQ32172 NM_001018067 NP_001018077 NM_001018068 NP_001018078 NM_001018069 NP_001018079 NM_015640 NP_056455
|
| Function |
May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:12505151}. Nucleus {ECO:0000269|PubMed:12505151}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:12505151}. Note=Also found in perinuclear regions.
|
| Tissue Specificity |
Expressed at high level in the heart, skeletal muscle and kidney, and at low levels in placenta, liver and brain. {ECO:0000269|PubMed:12505151}.
|