CDC14A

Gene Symbol CDC14A
Entrez Gene 8556
Alt Symbol cdc14, hCDC14
Species Human
Gene Type protein-coding
Description cell division cycle 14A
Other Description CDC10 (cell division cycle 10, S. cerevisiae, homolog)|CDC14 cell division cycle 14 homolog A|dual specificity protein phosphatase CDC14A
Swissprots O43171 O60728 B1AQ15 Q8IXX0 O60727 Q9UNH5 B1AQ14 A6MA65 Q52LH9
Accessions AAT38107 EAW72956 EAW72957 EAW72958 EAW72959 EAW72960 Q9UNH5 AA929031 AB209857 BAD93094 AF000367 AAB88277 AF064102 AAC16659 AF064103 AAC16660 AF122013 AAD49217 AK302310 BAG63648 AK310292 AK310657 BC038979 AAH38979 BC071578 BC093916 AAH93916 BC093918 AAH93918 BU609013 CB156695 DA461435 DA885382 DQ530256 ABF74568 XM_005271294 XP_005271351 XM_005271296 XP_005271353 XM_011542340 XP_011540642 XM_011542341 XP_011540643 XM_011542342 XP_011540644 XM_011542343 XP_011540645 XM_011542344 XP_011540646 XM_011542345 XP_011540647 XM_011542346 XP_011540648 NM_003672 NP_003663 NM_033312 NP_201569 NM_033313 NP_201570
Function Dual-specificity phosphatase. Required for centrosome separation and productive cytokinesis during cell division. Dephosphorylates SIRT2 around early anaphase. May dephosphorylate the APC subunit FZR1/CDH1, thereby promoting APC-FZR1 dependent degradation of mitotic cyclins and subsequent exit from mitosis. {ECO:0000269|PubMed:11901424, ECO:0000269|PubMed:12134069, ECO:0000269|PubMed:17488717, ECO:0000269|PubMed:9367992}.
Subcellular Location Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Note=Centrosomal during interphase, released into the cytoplasm at the onset of mitosis. Subsequently localizes to the midzone of the mitotic spindle.
Top Pathways Cell cycle

Cdc14a phosphatase (N-18) - sc-25952 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Cdc14a phosphatase (DCS-291) - sc-56260 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Cdc14a phosphatase (DCS-291): sc-56260. Western blot analysis of Cdc14a phosphatase expression in PANC-1 (A), A549 (B), HeLa (C) and A431 (D) whole cell lysates.

Cdc14a phosphatase (H-58) - sc-367957 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Cdc14a phosphatase (C-19) - sc-25954 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Cdc14A antibody - ab128649 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Cdc14A antibody (ab128649) at 1 µg/ml + RPMI-8226 cell lysate at 10 µg

Anti-Cdc14A antibody - ab172234 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Cdc14A antibody (ab172234) at 1 µg/mlLane 1 : Cdc14A-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H+L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-Cdc14A antibody [DCS-291] - ab10536 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal
Clone DCS-291

Anti-Cdc14A antibody - C-terminal - ab172951 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Cdc14A antibody - C-terminal (ab172951) at 1/100 dilution + A549 cell lysate at 35 µg

Anti-Cdc14 / CDC14A Antibody (aa1-379, AP) - LS-C254188 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa1-379, APC) - LS-C254189 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa431-531, clone 10B2171, Azide-free) - LS-C183508 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 10B2171

Anti-Cdc14 / CDC14A Antibody (aa1-379, Biotin) - LS-C254190 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa1-379, FITC) - LS-C254191 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa1-379, Azide-free, HRP) - LS-C254192 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa1-379, PE) - LS-C254193 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa384-433) - LS-C151688 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Cdc14 / CDC14A antibody Western Blot of RPMI-8226.

Anti-Cdc14 / CDC14A Antibody (aa472-500, AP) - LS-C254194 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa472-500, APC) - LS-C254195 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa472-500, Biotin) - LS-C254196 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa472-500, FITC) - LS-C254197 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa472-500, Azide-free, HRP) - LS-C254198 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa472-500, PE) - LS-C254199 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa1-379) - LS-C320215 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-Cdc14 / CDC14A Antibody (aa431-530) - LS-C306854 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-Cdc14 / CDC14A Antibody (aa472-500) - LS-C320216 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
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