CYP1A1

Gene Symbol CYP1A1
Entrez Gene 1543
Alt Symbol AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
Species Human
Gene Type protein-coding
Description cytochrome P450, family 1, subfamily A, polypeptide 1
Other Description CYPIA1|aryl hydrocarbon hydroxylase|cytochrome P1-450, dioxin-inducible|cytochrome P450 1A1|cytochrome P450 form 6|cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1|cytochrome P450-C|cytochrome P450-P1|flavoprotein-linked monooxygenase|xenobiotic monooxygenase
Swissprots A4F3V9 P04798 A4F3W0 Q53G18
Accessions AAK25727 ABK41999 CAA26458 CAA27843 EAW99314 EAW99315 P04798 AF040258 AF040259 AAD10199 AK223108 BAD96828 AK223113 BAD96833 AK310810 AK313880 BAG36606 AM233517 CAJ80720 AM233518 CAJ80721 AM233519 CAJ80722 AM233520 CAJ80723 AM236046 CAJ84703 AM236047 CAJ84704 AY310359 AAQ76692 AY871801 AAX62803 BC023019 AAH23019 DQ891515 ABM82441 DQ894706 ABM85632 K03191 AAA52139 M12079 AAA52152 XM_005254185 XP_005254242 NM_000499 NP_000490
Function Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Subcellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Tissue Specificity Lung, lymphocytes and placenta.
Top Pathways Steroid hormone biosynthesis, Chemical carcinogenesis, Ovarian steroidogenesis, Retinol metabolism, Tryptophan metabolism

CYP1A1 (A-9) - sc-393979 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP1A1 (A-9): sc-393979. Western blot analysis of CYP1A1 expression in HeLa (A), Neuro-2A (B) and C6 (C) whole cell lysates.

CYP1A1 (B-4) - sc-25304 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP1A1 (B-4): sc-25304. Western blot analysis of CYP1A1 expression in non-transfected: sc-117752 (A) and human CYP1A1 transfected: sc-114027 (B) 293T whole cell lysates.

CYP1A1 (1A3-03) - sc-101828 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP1A1 (1A3-03): sc-101828. Western blot analysis of CYP1A1 expression in non-transfected: sc-117752 (A) and human CYP1A1 transfected: sc-114027 (B) 293T whole cell lysates.

CYP1A1 (B-2) - sc-48432 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CYP1A1 (B-2): sc-48432. Western blot analysis of human recombinant CYP1A1 fusion protein.

CYP1A1 (G-18) - sc-9828 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CYP1A1 (G-18): sc-9828. Western blot analysis of CYP1A1 expression in non-transfected: sc-117752 (A) and human CYP1A1 transfected: sc-114027 (B) 293T whole cell lysates.

CYP1A1 (H-70) - sc-20772 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CYP1A1 (H-70) sc-20772. Immunofluorescence staining of normal mouse intestine frozen section showing cytoplasmic staining.

Anti-Cytochrome P450 1A1 + 1A2 antibody - ab136050 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome P450 1A1 + 1A2 antibody (ab136050) at 1/500 dilution + HeLa cell lysate at 30 µg

Anti-Cytochrome P450 1A1 + 1A2 antibody [MC1] - ab111868 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone MC1
ab111868 labelling Cytochrome P450 1A1 + 1A2 (green) in the cytoplasm and membrane of COS-7 cells by Immunocytochemistry/Immunofluorescence. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were incubated with the primary antibody (1:100 in 3% BSA-PBS) overnight at 4 ºC. A DyLight-conjugated anti-mouse IgG was used as the secondary antibody. Red (phalloidin) - F-actin, Blue -nuclei. Images were taken at a magnification of 60x.

Anti-Cytochrome P450 1A1 antibody - ab3568 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab3568 at a dilution of 1/500 staining MCF-7 cell extract by Western blot.

Anti-Cytochrome P450 1A1 antibody - ab171883 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Cytochrome P450 1A1 antibody (ab171883) at 1 µg/mlLane 1 : Cytochrome P450 1A1 transfected 293T cell lysateLane 2 : Non- transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-Cytochrome P450 1A1 antibody [6G5] - ab126828 from Abcam

Prices $384.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6G5
Overlay histogram showing A549 cells stained with ab126828 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab126828, 1/50 dilution) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-Cytochrome P450 1A1 antibody - C-terminal - ab79819 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Cytochrome P450 1A1 antibody - C-terminal (ab79819) at 1/50 dilution + K562 cell lysate at 35 µg

Anti-Cytochrome P450 1A1 antibody - C-terminal - ab195434 from Abcam

Prices $370.00
Sizes 25 µl
Host Rabbit
Clonality Polyclonal

Anti-CYP1A1 Antibody - LS-C6333 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP1A1 Antibody - LS-C14760 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP1A1 Antibody - LS-C22604 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CYP1A1 Antibody (aa277-294) - LS-C22605 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CYP1A1 Antibody (aa277-294) - LS-C22606 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CYP1A1 Antibody - LS-C22608 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CYP1A1 Antibody - LS-C64197 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP1A1 Antibody - LS-C86041 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP1A1 Antibody - LS-C86036 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP1A1 Antibody - LS-C128484 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CYP1A1 Antibody (aa251-300) - LS-C80418 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Hela cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-CYP1A1 Antibody (aa301-350) - LS-C80419 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.
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