| Gene Symbol |
CYP1A1
|
| Entrez Gene |
1543
|
| Alt Symbol |
AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 1, subfamily A, polypeptide 1
|
| Other Description |
CYPIA1|aryl hydrocarbon hydroxylase|cytochrome P1-450, dioxin-inducible|cytochrome P450 1A1|cytochrome P450 form 6|cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1|cytochrome P450-C|cytochrome P450-P1|flavoprotein-linked monooxygenase|xenobiotic monooxygenase
|
| Swissprots |
A4F3V9 P04798 A4F3W0 Q53G18
|
| Accessions |
AAK25727 ABK41999 CAA26458 CAA27843 EAW99314 EAW99315 P04798 AF040258 AF040259 AAD10199 AK223108 BAD96828 AK223113 BAD96833 AK310810 AK313880 BAG36606 AM233517 CAJ80720 AM233518 CAJ80721 AM233519 CAJ80722 AM233520 CAJ80723 AM236046 CAJ84703 AM236047 CAJ84704 AY310359 AAQ76692 AY871801 AAX62803 BC023019 AAH23019 DQ891515 ABM82441 DQ894706 ABM85632 K03191 AAA52139 M12079 AAA52152 XM_005254185 XP_005254242 NM_000499 NP_000490
|
| Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Tissue Specificity |
Lung, lymphocytes and placenta.
|
| Top Pathways |
Steroid hormone biosynthesis, Chemical carcinogenesis, Ovarian steroidogenesis, Retinol metabolism, Tryptophan metabolism
|