SGCB

Gene Symbol	SGCB
Entrez Gene	6443
Alt Symbol	A3b, LGMD2E, SGC
Species	Human
Gene Type	protein-coding
Description	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)
Other Description	43 kDa dystrophin-associated glycoprotein|43DAG|beta-SG|beta-sarcoglycan|beta-sarcoglycan(43kD dystrophin-associated glycoprotein)|limb girdle muscular dystrophy 2E (non-linked families)
Swissprots	Q16585 B7Z635 O00661
Accessions	AAB46956 CAA70920 EAX05429 EAX05430 Q16585 AK094731 AK289892 BAF82581 AK299765 BAH13121 BC020709 AAH20709 BC048972 BT019433 AAV38240 CA449352 CN483961 CR456810 CAG33091 DQ893140 ABM84066 DQ896425 ABM87424 EU176433 ABW03884 U29586 AAB41291 U31116 AAA87034 XM_006714049 XP_006714112 XM_011534403 XP_011532705 XM_011534404 XP_011532706 NM_000232 NP_000223
Function	Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Subcellular Location	Cell membrane, sarcolemma {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton {ECO:0000250}.
Tissue Specificity	Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver.
Top Pathways	Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

β-sarcoglycan siRNA (h) - sc-43418 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

β-sarcoglycan shRNA Plasmid (h) - sc-43418-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

β-sarcoglycan shRNA (h) Lentiviral Particles - sc-43418-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

beta Sarcoglycan RNAi - H00006443-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU017521 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19219 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19219 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

SGCB siRNA (Human) - CRH4354 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SGCB - MBS8223585 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human SGCB (NM_000232.4) - SHH406172 from Creative biogene Category siRNA Species Reactivities Human

Human SGCB siRNA - orb264856 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

SGCB shRNA Plasmid (Human) - CHH4354 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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