| Gene Symbol |
DESI1
|
| Entrez Gene |
27351
|
| Alt Symbol |
D15Wsu75e, DESI2, DJ347H13.4, DeSI-1, FAM152B, PPPDE2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
desumoylating isopeptidase 1
|
| Other Description |
PPPDE peptidase domain containing 2|PPPDE peptidase domain-containing protein 2|desumoylating isopeptidase 2|family with sequence similarity 152, member B
|
| Swissprots |
Q6ICB0
|
| Accessions |
EAW60445 Q6ICB0 AF038183 AK090725 BC008357 BC039554 BC093956 AAH93956 BC112179 AAI12180 BC171724 BX403547 BX478162 CR456458 CAG30344 XM_005261571 XP_005261628 XM_011530157 XP_011528459 NM_015704 NP_056519
|
| Function |
Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
|
![Western Blot: PPPDE2 Overexpression Lysate (Adult Normal) [NBL1-10484] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PPPDE2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/7374_PPPDE2%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-10484-img0002.jpg)