Gene Symbol | DESI1 |
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Entrez Gene | 27351 |
Alt Symbol | D15Wsu75e, DESI2, DJ347H13.4, DeSI-1, FAM152B, PPPDE2 |
Species | Human |
Gene Type | protein-coding |
Description | desumoylating isopeptidase 1 |
Other Description | PPPDE peptidase domain containing 2|PPPDE peptidase domain-containing protein 2|desumoylating isopeptidase 2|family with sequence similarity 152, member B |
Swissprots | Q6ICB0 |
Accessions | EAW60445 Q6ICB0 AF038183 AK090725 BC008357 BC039554 BC093956 AAH93956 BC112179 AAI12180 BC171724 BX403547 BX478162 CR456458 CAG30344 XM_005261571 XP_005261628 XM_011530157 XP_011528459 NM_015704 NP_056519 |
Function | Protease which deconjugates SUMO1, SUMO2 and SUMO3 from some substrate proteins. Has isopeptidase but not SUMO-processing activity. Desumoylates ZBTB46 (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
PPPDE2 CRISPR/Cas9 KO Plasmid (h) - sc-406172 from Santa Cruz Biotechnology
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PPPDE2 HDR Plasmid (h) - sc-406172-HDR from Santa Cruz Biotechnology
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PPPDE2 Double Nickase Plasmid (h) - sc-406172-NIC from Santa Cruz Biotechnology
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PPPDE2 Double Nickase Plasmid (h2) - sc-406172-NIC-2 from Santa Cruz Biotechnology
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PPPDE2 CRISPR Activation Plasmid (h) - sc-406172-ACT from Santa Cruz Biotechnology
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PPPDE2 CRISPR Activation Plasmid (h2) - sc-406172-ACT-2 from Santa Cruz Biotechnology
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PPPDE2 Lentiviral Activation Particles (h) - sc-406172-LAC from Santa Cruz Biotechnology
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PPPDE2 Lentiviral Activation Particles (h2) - sc-406172-LAC-2 from Santa Cruz Biotechnology
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PPPDE2 siRNA (h) - sc-77087 from Santa Cruz Biotechnology
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PPPDE2 shRNA Plasmid (h) - sc-77087-SH from Santa Cruz Biotechnology
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PPPDE2 shRNA (h) Lentiviral Particles - sc-77087-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU119861 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17320 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17320 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00405 from Sigma-Aldrich
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DESI1 siRNA (Human) - CRH9100 from Cohesion Biosciences
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DESI1 - MBS8230423 from MyBioSource
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PPPDE2 CRISPR/Cas9 KO Plasmid (h2) - sc-406172-KO-2 from Santa Cruz Biotechnology
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PPPDE2 HDR Plasmid (h2) - sc-406172-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human PPPDE2 (NM_015704.2) - SHH381700 from Creative biogene
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Human DESI1 siRNA - orb269602 from Biorbyt
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DESI1 shRNA Plasmid (Human) - CHH9100 from Cohesion Biosciences
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DESI1 miRNA 3'UTR clone - MiUTR3H-13333 from Creative biogene
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