| Gene Symbol | CNN1 |
|---|---|
| Entrez Gene | 1264 |
| Alt Symbol | HEL-S-14, SMCC, Sm-Calp |
| Species | Human |
| Gene Type | protein-coding |
| Description | calponin 1, basic, smooth muscle |
| Other Description | basic calponin|calponin H1, smooth muscle|calponin-1|calponins, basic|epididymis secretory protein Li 14 |
| Swissprots | Q8IY93 Q99438 B4DUX6 P51911 Q15416 O00638 B2R868 |
| Accessions | BAA19538 EAW84228 EAW84229 P51911 AK223234 BAD96954 AK300837 BAG62488 AK301888 BAH13577 AK313255 BAG36065 AK316406 BAH14777 BC022015 AAH22015 BC036307 AAH36307 BG718473 D17408 BAA04231 D86058 BAA12983 EU794601 ACJ13655 HQ448227 ADQ32707 S80560 AAB35751 U37019 AAC51780 XM_005259741 XP_005259798 XM_011527689 XP_011525991 XM_011527690 XP_011525992 XM_011527691 XP_011525993 NM_001299 NP_001290 NM_001308341 NP_001295270 NM_001308342 NP_001295271 |
| Function | Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). {ECO:0000250}. |
| Tissue Specificity | Smooth muscle, and tissues containing significant amounts of smooth muscle. |
Calponin 1 CRISPR/Cas9 KO Plasmid (h) - sc-401397 from Santa Cruz Biotechnology
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Calponin 1 HDR Plasmid (h) - sc-401397-HDR from Santa Cruz Biotechnology
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Calponin 1 Double Nickase Plasmid (h) - sc-401397-NIC from Santa Cruz Biotechnology
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Calponin 1 Double Nickase Plasmid (h2) - sc-401397-NIC-2 from Santa Cruz Biotechnology
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Calponin 1 CRISPR Activation Plasmid (h) - sc-401397-ACT from Santa Cruz Biotechnology
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Calponin 1 CRISPR Activation Plasmid (h2) - sc-401397-ACT-2 from Santa Cruz Biotechnology
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Calponin 1 Lentiviral Activation Particles (h) - sc-401397-LAC from Santa Cruz Biotechnology
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Calponin 1 Lentiviral Activation Particles (h2) - sc-401397-LAC-2 from Santa Cruz Biotechnology
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Calponin 1 siRNA (h) - sc-43273 from Santa Cruz Biotechnology
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Calponin 1 shRNA Plasmid (h) - sc-43273-SH from Santa Cruz Biotechnology
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Calponin 1 shRNA (h) Lentiviral Particles - sc-43273-V from Santa Cruz Biotechnology
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Calponin 1/2/3 siRNA (h) - sc-43657 from Santa Cruz Biotechnology
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Calponin 1/2/3 shRNA Plasmid (h) - sc-43657-SH from Santa Cruz Biotechnology
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Calponin 1/2/3 shRNA (h) Lentiviral Particles - sc-43657-V from Santa Cruz Biotechnology
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Calponin 1 RNAi - H00001264-R01 from Novus Biologicals
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MISSION® esiRNA - EHU034001 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN6310 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6310 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05310 from Sigma-Aldrich
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CNN1 siRNA (Human) - CRH0884 from Cohesion Biosciences
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CNN1 - MBS8205606 from MyBioSource
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shRNA set against Human CNN1 (NM_001299.4) - SHH266309 from Creative biogene
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shRNA set against Human CNN1(NM_001299.4) - SHG187093 from Creative biogene
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Human CNN1 siRNA - orb261386 from Biorbyt
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CNN1 shRNA Plasmid (Human) - CHH0884 from Cohesion Biosciences
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