CNN1

Gene Symbol	CNN1
Entrez Gene	1264
Alt Symbol	HEL-S-14, SMCC, Sm-Calp
Species	Human
Gene Type	protein-coding
Description	calponin 1, basic, smooth muscle
Other Description	basic calponin\|calponin H1, smooth muscle\|calponin-1\|calponins, basic\|epididymis secretory protein Li 14
Swissprots	Q8IY93 Q99438 B4DUX6 P51911 Q15416 O00638 B2R868
Accessions	BAA19538 EAW84228 EAW84229 P51911 AK223234 BAD96954 AK300837 BAG62488 AK301888 BAH13577 AK313255 BAG36065 AK316406 BAH14777 BC022015 AAH22015 BC036307 AAH36307 BG718473 D17408 BAA04231 D86058 BAA12983 EU794601 ACJ13655 HQ448227 ADQ32707 S80560 AAB35751 U37019 AAC51780 XM_005259741 XP_005259798 XM_011527689 XP_011525991 XM_011527690 XP_011525992 XM_011527691 XP_011525993 NM_001299 NP_001290 NM_001308341 NP_001295270 NM_001308342 NP_001295271
Function	Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity). {ECO:0000250}.
Tissue Specificity	Smooth muscle, and tissues containing significant amounts of smooth muscle.

Calponin 1 (CALP) - sc-58707 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Calponin 1 (CALP): sc-58707. Western blot analysis of Calponin 1 expression in human breast tumor tissue extract.

Calponin 1 (N-15)-R - sc-16604-R from Santa Cruz Biotechnology

Prices	$61.00
Sizes	100 µg/0.5 ml
Host	Rabbit
Clonality	Polyclonal

Calponin 1 (SPM169) - sc-52992 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Calponin 1 (SPM169): sc-52992. Western blot analysis of Calponin 1 expression in human breast tumor tissue extract.

Calponin 1 (0.N.39) - sc-70487 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Calponin 1 (0.N.39): sc-70487. Western blot analysis of Calponin 1 expression in human breast tumor tissue extract.

Calponin 1/2/3 (E-4) - sc-136986 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Calponin 1/2/3 (E-4): sc-136986. Western blot analysis of human recombinant Calponin 1/2/3.

Calponin 1/2/3 (FL-297) - sc-28545 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Rabbit
Clonality	Polyclonal

Calponin 1/2/3 (FL-297): sc-28545. Western blot analysis of Calponin 2 expression in non-transfected: sc-117752 (A) and human Calponin 2 transfected: sc-112525 (B) 293T whole cell lysates.

Calponin 1/2/3 (G-10) - sc-136987 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Calponin 1/2/3 (G-10): sc-136987. Western blot analysis of Calponin 1/2/3 expression in 293T (A) and JEG-3 (B) whole cell lysates.

Calponin 1/2/3 (H-3) - sc-133188 from Santa Cruz Biotechnology

Prices	$279.00
Sizes	200 µg/ml
Host	Mouse
Clonality	Monoclonal

Calponin 1/2/3 (H-3): sc-133188. Western blot analysis of human recombinant Calponin 1/2/3.

Anti-Calponin antibody - ab78491 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

All lanes : Anti-Calponin antibody (ab78491) at 1 µg/mlLane 1 : Heart (Human) Tissue Lysate - adult normal tissue (ab29431)Lane 2 : Small Intestine (Human) Tissue Lysate - adult normal tissue (ab29276)Lane 3 : Bladder (Human) Tissue Lysate - adult normal tissue (ab44654)Lane 4 : Colon tissue lysate (Human) Tissue Lysate - adult normal tissue (ab30051)Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Calponin antibody - ab84482 from Abcam

Prices	$376.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

Anti-Calponin antibody (ab84482) at 1/1000 dilution + Human fetal stomach lysates

Anti-Calponin antibody - ab111183 from Abcam

Prices	$370.00
Sizes	200 µl
Host	Rabbit
Clonality	Polyclonal

Anti-Calponin antibody [26A11] - ab50842 from Abcam

Prices	$376.00
Sizes	500 µg
Host	Mouse
Clonality	Monoclonal
Clone	26A11

Immunohistochemical staining of basic Calponin in normal human appendix, using ab50842 at a 1/25 dilution. Note cytoplasmic staining of smooth muscle.

Anti-Calponin antibody [CALP] - ab700 from Abcam

Prices	$395.00
Sizes	500 µl
Host	Mouse
Clonality	Monoclonal
Clone	CALP

ab700 at a 1/50 dilution staining rat heart tissue sections by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). The tissue was formaldehyde fixed prior to incubation with the antibody overnight at 4°C. An Alex-Fluor ® 488 conjugated goat anti-mouse antibody was used as the secondary. The image was taken with a confocal laser scanning microscope with an additional Differential Interference Contrast (DIC) mode and shows stained Calponin (smooth muscle cells-green) and counterstained nuclei (DAPI-blue) (left panel).DIC (phase) image of the same tissue (right panel) confirm the localization of the calponin staining in the arterial smooth muscle in the heart tissue with very little background.See Abreview

Anti-Calponin antibody [CALP], prediluted - ab1408 from Abcam

Prices	$370.00
Sizes	6 ml
Host	Mouse
Clonality	Monoclonal
Clone	CALP

Anti-Calponin antibody [EP798Y] - ab46794 from Abcam

Prices	$401.00
Sizes	100 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EP798Y

Anti-Calponin antibody [EP798Y] (ab46794) at 1/20000 dilution + Human bladder lysate at 10 µgSecondaryGoat anti-rabbit HRP at 1/2000 dilutionObserved band size : 34 kDa (why is the actual band size different from the predicted?)

Anti-Calponin antibody - C-terminal - ab203047 from Abcam

Prices	$359.00
Sizes	100 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of formalin-fixed paraffin-embedded mouse stomach tissue labeling Calponin with ab203047 at 1/200 dilution.

Anti-Calponin antibody - N-terminal - ab175572 from Abcam

Prices	$384.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human lung carcinoma tissue labeling Calponin with ab175572 at 1/10 dilution followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-CNN1 / Calponin Antibody (aa17-47) - LS-C168279 from LifeSpan Bioscience

Prices	$295.00
Sizes	400 µl
Host	Rabbit
Clonality	Polyclonal

Formalin-fixed and paraffin-embedded human lung carcinoma with Calponin-1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Anti-CNN1 / Calponin Antibody (C-Terminus, clone SP193) - LS-C210420 from LifeSpan Bioscience

Prices	$530.00
Sizes	500 µl
Host	Rabbit
Clonality	Monoclonal
Clone	SP193

Immunohistochemistry of Human colon stained with anti-calponin-1 antibody

Anti-CNN1 / Calponin Antibody (C-Terminus, clone EP798Y) IHC-plus™ - LS-B7497 from LifeSpan Bioscience

Prices	$395.00
Sizes	50 µl
Host	Rabbit
Clonality	Monoclonal
Clone	EP798Y

Anti-CNN1 / Calponin antibody IHC of human prostate, smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7497 dilution 1:50.

Anti-CNN1 / Calponin Antibody IHC-plus™ - LS-B3719 from LifeSpan Bioscience

Prices	$395.00
Sizes	50 µg
Host	Goat
Clonality	Polyclonal

Anti-CNN1 / Calponin Antibody (C-Terminus, clone SP180) - LS-C210409 from LifeSpan Bioscience

Prices	$530.00
Sizes	500 µl
Host	Rabbit
Clonality	Monoclonal
Clone	SP180

Immunohistochemistry of Human Prostate stained with anti-Calponin-1 antibody

Anti-CNN1 / Calponin Antibody (Internal, clone SP181) - LS-C210408 from LifeSpan Bioscience

Prices	$530.00
Sizes	500 µl
Host	Rabbit
Clonality	Monoclonal
Clone	SP181

Immunohistochemistry of Human Kidney stained with anti-Calponin-1 antibody

Anti-CNN1 / Calponin Antibody (aa283-297) - LS-C313323 from LifeSpan Bioscience

Prices	$305.00
Sizes	100 µg
Host	Rabbit
Clonality	Polyclonal

CNN1 / Calponin antibody. IHC(P): Human Placenta Tissue.

Anti-CNN1 / Calponin Antibody (clone CALP, Azide-free) - LS-C87587 from LifeSpan Bioscience

Prices	$515.00, $655.00
Sizes	100 µg, 200 µg
Host	Mouse
Clonality	Monoclonal
Clone	CALP

Formalin-fixed, paraffin-embedded human breast stained with peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of myoepithelial cells in the lactiferous ducts.

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