ZNRF3

Gene Symbol ZNRF3
Entrez Gene 84133
Alt Symbol BK747E2.3, RNF203
Species Human
Gene Type protein-coding
Description zinc and ring finger 3
Other Description CTA-292E10.6|E3 ubiquitin-protein ligase ZNRF3|RING finger protein 203|novel C3HC4 type Zinc finger (ring finger)|zinc/RING finger protein 3
Swissprots Q6NTF8 B3KU18 Q8WU18 Q9ULT6 Q6ICH1
Accessions EAW59767 EAW59768 EAW59769 EAW59770 Q9ULT6 AB051436 BAB33319 AI244417 AK022809 AK025710 AK096397 BAG53280 BC009252 AAH09252 BC021570 AAH21570 BC042614 BC051344 BC069019 AAH69019 BC094857 AAH94857 BC167805 AAI67805 CR456397 CAG30283 CU012955 CAK54386 CU013243 CAK54685 HG512185 HG512186 HG512188 HG512189 XM_005261773 XP_005261830 XM_011530434 XP_011528736 XM_011530435 XP_011528737 XM_011530436 XP_011528738 XM_011530437 XP_011528739 XM_011530438 XP_011528740 XM_011530439 XP_011528741 XM_011530440 XP_011528742 XM_011530441 XP_011528743 NM_001206998 NP_001193927 NM_032173 NP_115549
Function E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non- canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. {ECO:0000269|PubMed:22575959}.
Subcellular Location Cell membrane {ECO:0000269|PubMed:22575959}; Single-pass type I membrane protein {ECO:0000269|PubMed:22575959}.

ZNRF3 CRISPR/Cas9 KO Plasmid (h) - sc-418162 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNRF3 HDR Plasmid (h) - sc-418162-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNRF3 Double Nickase Plasmid (h) - sc-418162-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNRF3 Double Nickase Plasmid (h2) - sc-418162-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNRF3 CRISPR Activation Plasmid (h) - sc-418162-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNRF3 CRISPR Activation Plasmid (h2) - sc-418162-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNRF3 Lentiviral Activation Particles (h) - sc-418162-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNRF3 Lentiviral Activation Particles (h2) - sc-418162-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ZNRF3 siRNA (h) - sc-77014 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNRF3 shRNA Plasmid (h) - sc-77014-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ZNRF3 shRNA (h) Lentiviral Particles - sc-77014-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU136411 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN23785 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23785 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ZNRF3 siRNA (Human) - CRJ3314 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZNRF3 - MBS8229758 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ZNRF3 (NM_032173.3) - SHH455700 from Creative biogene

Category siRNA
Species Reactivities Human

Human ZNRF3 siRNA - orb273815 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ZNRF3 shRNA Plasmid (Human) - CHJ3314 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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