| Gene Symbol |
KAT6B
|
| Entrez Gene |
23522
|
| Alt Symbol |
GTPTS, MORF, MOZ2, MYST4, ZC2HC6B, qkf, querkopf
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
K(lysine) acetyltransferase 6B
|
| Other Description |
MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4|MOZ-related factor|MYST histone acetyltransferase (monocytic leukemia) 4|MYST-4|histone acetyltransferase KAT6B|histone acetyltransferase MORF|histone acetyltransferase MOZ2|histone acetyltransferase MYST4|monocytic leukemia zinc finger protein-related factor
|
| Swissprots |
Q9UKW2 Q8WYB5 Q9UKX0 Q8WU81 Q86Y05 O15087 Q9UKW3
|
| Accessions |
EAW54557 EAW54558 EAW54559 Q8WYB5 AA416904 AB002381 BAA20837 AF113514 AAF00095 AF119230 AAF00099 AF119231 AAF00100 AF217500 AAL56647 AK074816 AL832065 CAH10408 BC014143 AAH14143 BC021128 AAH21128 BC048199 AAH48199 BC150270 AAI50271 BC150618 AAI50619 DA488537 XM_005269664 XP_005269721 XM_011548776 XP_011547078 NM_001256468 NP_001243397 NM_001256469 NP_001243398 NM_012330 NP_036462
|
| Function |
Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. {ECO:0000269|PubMed:10497217, ECO:0000269|PubMed:11965546, ECO:0000269|PubMed:16387653}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitously expressed, with high levels in heart, pancreas, testis and ovary. {ECO:0000269|PubMed:10497217}.
|