| Gene Symbol |
TGIF2
|
| Entrez Gene |
60436
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
TGFB-induced factor homeobox 2
|
| Other Description |
5'-TG-3' interacting factor 2|TGF(beta)-induced transcription factor 2|TGF-beta-induced transcription factor 2|TGFB-induced factor 2 (TALE family homeobox)|homeobox protein TGIF2|transcription growth factor-beta-induced factor 2
|
| Swissprots |
E1P5T9 Q9GZN2 H0YNI0 B2R9U3
|
| Accessions |
CAF86813 EAW76127 EAW76128 Q9GZN2 AB042646 BAB16424 AF055012 AK074802 BAC11216 AK074829 AK313919 BAG36640 AL705108 BC006549 AAH06549 BC012816 AAH12816 BG723865 BI869422 BP353213 BQ881960 DA438831 DQ893400 ABM84326 DQ896720 ABM87719 NM_001199513 NP_001186442 NM_001199514 NP_001186443 NM_001199515 NP_001186444 NM_021809 NP_068581
|
| Function |
Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins. {ECO:0000269|PubMed:11427533}.
|
| Subcellular Location |
Nucleus. Note=Excluded from nucleoli.
|
| Tissue Specificity |
Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate.
|
![Western Blot: TGF beta induced factor 2 Overexpression Lysate (Adult Normal) [NBL1-16864] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TGF beta induced factor 2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6539_TGF%2520beta%2520induced%2520factor%25202%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16864-img0002.jpg)