Gene Symbol | TGIF2 |
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Entrez Gene | 60436 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | TGFB-induced factor homeobox 2 |
Other Description | 5'-TG-3' interacting factor 2|TGF(beta)-induced transcription factor 2|TGF-beta-induced transcription factor 2|TGFB-induced factor 2 (TALE family homeobox)|homeobox protein TGIF2|transcription growth factor-beta-induced factor 2 |
Swissprots | E1P5T9 Q9GZN2 H0YNI0 B2R9U3 |
Accessions | CAF86813 EAW76127 EAW76128 Q9GZN2 AB042646 BAB16424 AF055012 AK074802 BAC11216 AK074829 AK313919 BAG36640 AL705108 BC006549 AAH06549 BC012816 AAH12816 BG723865 BI869422 BP353213 BQ881960 DA438831 DQ893400 ABM84326 DQ896720 ABM87719 NM_001199513 NP_001186442 NM_001199514 NP_001186443 NM_001199515 NP_001186444 NM_021809 NP_068581 |
Function | Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated SMAD proteins. Probably represses transcription via the recruitment of histone deacetylase proteins. {ECO:0000269|PubMed:11427533}. |
Subcellular Location | Nucleus. Note=Excluded from nucleoli. |
Tissue Specificity | Widely expressed. Highly expressed in heart, kidney and testis. Weakly expressed in brain and prostate. |
TGIF2 CRISPR/Cas9 KO Plasmid (h) - sc-416231 from Santa Cruz Biotechnology
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TGIF2 HDR Plasmid (h) - sc-416231-HDR from Santa Cruz Biotechnology
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TGIF2 Double Nickase Plasmid (h) - sc-416231-NIC from Santa Cruz Biotechnology
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TGIF2 Double Nickase Plasmid (h2) - sc-416231-NIC-2 from Santa Cruz Biotechnology
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TGIF2 CRISPR Activation Plasmid (h) - sc-416231-ACT from Santa Cruz Biotechnology
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TGIF2 CRISPR Activation Plasmid (h2) - sc-416231-ACT-2 from Santa Cruz Biotechnology
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TGIF2 Lentiviral Activation Particles (h) - sc-416231-LAC from Santa Cruz Biotechnology
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TGIF2 Lentiviral Activation Particles (h2) - sc-416231-LAC-2 from Santa Cruz Biotechnology
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TGIF2 siRNA (h) - sc-63123 from Santa Cruz Biotechnology
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TGIF2 shRNA Plasmid (h) - sc-63123-SH from Santa Cruz Biotechnology
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TGIF2 shRNA (h) Lentiviral Particles - sc-63123-V from Santa Cruz Biotechnology
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TGF beta induced factor 2 RNAi - H00060436-R01V from Novus Biologicals
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TGF beta induced factor 2 RNAi - H00060436-R01 from Novus Biologicals
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MISSION® esiRNA - EHU024421 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN21279 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21279 from Sigma-Aldrich
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TGIF2 siRNA (Human) - CRJ1793 from Cohesion Biosciences
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TGIF2 - MBS8240544 from MyBioSource
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shRNA set against Human TGIF2 (NM_021809.6) - SHH426492 from Creative biogene
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Human TGIF2 siRNA - orb272294 from Biorbyt
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TGIF2 shRNA Plasmid (Human) - CHJ1793 from Cohesion Biosciences
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