Gene Symbol | NUDT11 |
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Entrez Gene | 55190 |
Alt Symbol | APS1, ASP1, DIPP3b, DIPP3beta, hDIPP3beta |
Species | Human |
Gene Type | protein-coding |
Description | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
Other Description | DIPP-3-beta|DIPP3-beta|diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 3-beta|diadenosine hexaphosphate hydrolase (AMP-forming)|diphosphoinositol polyphosphate phosphohydrolase 3, beta|diphosphoinositol polyphosphate phosphohydrolase 3-beta|hAps1|nucleoside diphosphate-linked moiety X motif 11|nudix motif 11 |
Swissprots | Q9NVN0 Q96G61 |
Accessions | EAW89906 Q96G61 AK001490 BAA91720 AM392606 CAL37484 BC009942 AAH09942 BX419815 NM_018159 NP_060629 |
Function | Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12121577}. |
Tissue Specificity | Mainly expressed in testis and, at lower level in brain. According to PubMed:12121577, it is also expressed in pancreas and weakly expressed in thymus, prostate, ovary, lung, small intestine and heart. {ECO:0000269|PubMed:12105228, ECO:0000269|PubMed:12121577}. |
NUDT11 antibody - 10912-1-AP from Acris Antibodies
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NUDT11 antibody - H00055190-B01P from Acris Antibodies
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NUDT11 antibody - 10912-1-AP from Proteintech Group
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Anti-NUDT11 monoclonal antibody - DCABH-201071 from Creative Diagnostics
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NUDT11 Antibody - CSB-PA836216LA01HU from Cusabio
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NUDT11 Antibody,HRP conjugated - CSB-PA836216LB01HU from Cusabio
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NUDT11 Antibody,FITC conjugated - CSB-PA836216LC01HU from Cusabio
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NUDT11 Antibody,Biotin conjugated - CSB-PA836216LD01HU from Cusabio
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NUDT11 Antibody - NBP2-49265 from Novus Biologicals
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NUDT11 antibody (FITC) - orb355901 from Biorbyt
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anti-NUDT11 antibody - A005899 from Biobool
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NUDT11, Polyclonal Antibody - MBS1494854 from MyBioSource
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NUDT11, Polyclonal Antibody - MBS1494657 from MyBioSource
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NUDT11, Polyclonal Antibody - MBS1499340 from MyBioSource
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NUDT11, Polyclonal Antibody - MBS7602132 from MyBioSource
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NUDT11, Polyclonal Antibody - MBS1494258 from MyBioSource
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Anti-NUDT11 Antibody (HRP) - LS-C378344 from LifeSpan Bioscience
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Anti-NUDT11 Antibody (FITC) - LS-C378346 from LifeSpan Bioscience
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Anti-NUDT11 Antibody (Biotin) - LS-C378347 from LifeSpan Bioscience
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Anti-NUDT11 Antibody - LS-C378340 from LifeSpan Bioscience
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NUDT11 antibody (HRP) - orb355902 from Biorbyt
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Rabbit anti-Human NUDT11 polyclonal antibody - CABT-B9671 from Creative Diagnostics
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