Gene Symbol |
TRPC7
|
Entrez Gene |
57113
|
Alt Symbol |
TRP7
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
transient receptor potential cation channel, subfamily C, member 7
|
Other Description |
TRP-7|hTRP7|likley ortholog of mouse transient receptor potential cation channel, subfamily C, member 7|putative capacitative calcium channel|short transient receptor potential channel 7|transient receptor protein 7
|
Swissprots |
Q8IWP7 Q70T26 F5H5U9 Q9HCX4 A1A4Z4
|
Accessions |
AAF23315 EAW62187 EAW62188 EAW62189 EAW62190 EAW62191 EAW62192 Q9HCX4 AJ272034 CAC03489 AJ421783 CAD19069 AJ549088 CAD70161 AJ549089 CAD70162 AJ549090 CAD70163 AY167926 AAO12124 AY167927 AAO12125 BC128185 AAI28186 BC128186 AAI28187 BI826927 DR002519 XM_011543516 XP_011541818 XM_011543517 XP_011541819 XM_011543518 XP_011541820 NM_001167576 NP_001161048 NM_001167577 NP_001161049 NM_020389 NP_065122
|
Function |
Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. {ECO:0000250}.
|
Subcellular Location |
Cell membrane {ECO:0000269|PubMed:21402151}; Multi-pass membrane protein {ECO:0000269|PubMed:21402151}. Nucleus envelope {ECO:0000269|PubMed:21402151}.
|