Gene Symbol | TRPC7 |
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Entrez Gene | 57113 |
Alt Symbol | TRP7 |
Species | Human |
Gene Type | protein-coding |
Description | transient receptor potential cation channel, subfamily C, member 7 |
Other Description | TRP-7|hTRP7|likley ortholog of mouse transient receptor potential cation channel, subfamily C, member 7|putative capacitative calcium channel|short transient receptor potential channel 7|transient receptor protein 7 |
Swissprots | Q8IWP7 Q70T26 F5H5U9 Q9HCX4 A1A4Z4 |
Accessions | AAF23315 EAW62187 EAW62188 EAW62189 EAW62190 EAW62191 EAW62192 Q9HCX4 AJ272034 CAC03489 AJ421783 CAD19069 AJ549088 CAD70161 AJ549089 CAD70162 AJ549090 CAD70163 AY167926 AAO12124 AY167927 AAO12125 BC128185 AAI28186 BC128186 AAI28187 BI826927 DR002519 XM_011543516 XP_011541818 XM_011543517 XP_011541819 XM_011543518 XP_011541820 NM_001167576 NP_001161048 NM_001167577 NP_001161049 NM_020389 NP_065122 |
Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:21402151}; Multi-pass membrane protein {ECO:0000269|PubMed:21402151}. Nucleus envelope {ECO:0000269|PubMed:21402151}. |
TRPC7 CRISPR/Cas9 KO Plasmid (h) - sc-403911 from Santa Cruz Biotechnology
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TRPC7 HDR Plasmid (h) - sc-403911-HDR from Santa Cruz Biotechnology
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TRPC7 Double Nickase Plasmid (h) - sc-403911-NIC from Santa Cruz Biotechnology
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TRPC7 Double Nickase Plasmid (h2) - sc-403911-NIC-2 from Santa Cruz Biotechnology
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TRPC7 CRISPR Activation Plasmid (h) - sc-403911-ACT from Santa Cruz Biotechnology
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TRPC7 CRISPR Activation Plasmid (h2) - sc-403911-ACT-2 from Santa Cruz Biotechnology
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TRPC7 Lentiviral Activation Particles (h) - sc-403911-LAC from Santa Cruz Biotechnology
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TRPC7 Lentiviral Activation Particles (h2) - sc-403911-LAC-2 from Santa Cruz Biotechnology
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TRPC7 siRNA (h) - sc-106641 from Santa Cruz Biotechnology
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TRPC7 shRNA Plasmid (h) - sc-106641-SH from Santa Cruz Biotechnology
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TRPC7 shRNA (h) Lentiviral Particles - sc-106641-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU078231 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22057 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22057 from Sigma-Aldrich
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TRPC7 siRNA (Human) - CRJ1330 from Cohesion Biosciences
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TRPC7 - MBS8226724 from MyBioSource
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shRNA set against Human Trpc7 (NM_020389.2) - SHH435608 from Creative biogene
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Human TRPC7 siRNA - orb271831 from Biorbyt
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TRPC7 shRNA Plasmid (Human) - CHJ1330 from Cohesion Biosciences
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TRPC7 miRNA 3'UTR clone - MiUTR3H-16429 from Creative biogene
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