Gene Symbol | ZP2 |
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Entrez Gene | 7783 |
Alt Symbol | ZPA, Zp-2 |
Species | Human |
Gene Type | protein-coding |
Description | zona pellucida glycoprotein 2 (sperm receptor) |
Other Description | zona pellucida glycoprotein ZP2|zona pellucida protein A|zona pellucida sperm-binding protein 2 |
Swissprots | Q4VAN9 Q4VAP1 Q4VAP0 B2R7J2 Q05996 |
Accessions | AAB67599 EAW66859 EAW66860 Q05996 AK293805 BAG57212 AK308820 AK310454 AK313003 BAG35839 BC096304 AAH96304 BC096305 AAH96305 BC096306 AAH96306 BC096307 AAH96307 M90366 AAA61335 XM_011545942 XP_011544244 NM_001290104 NP_001277033 NM_003460 NP_003451 |
Function | The mammalian zona pellucida, which mediates species- specific sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy, is composed of three to four glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor. |
Subcellular Location | Processed zona pellucida sperm-binding protein 2: Secreted, extracellular space, extracellular matrix. Note=The glycoproteinaceous translucent extracellular matrix that surrounds the mammalian oocyte is called zona pellucida. |
Tissue Specificity | Oocytes. |
ZP2 CRISPR/Cas9 KO Plasmid (h) - sc-408390 from Santa Cruz Biotechnology
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ZP2 HDR Plasmid (h) - sc-408390-HDR from Santa Cruz Biotechnology
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ZP2 Double Nickase Plasmid (h) - sc-408390-NIC from Santa Cruz Biotechnology
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ZP2 Double Nickase Plasmid (h2) - sc-408390-NIC-2 from Santa Cruz Biotechnology
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ZP2 CRISPR Activation Plasmid (h) - sc-408390-ACT from Santa Cruz Biotechnology
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ZP2 CRISPR Activation Plasmid (h2) - sc-408390-ACT-2 from Santa Cruz Biotechnology
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ZP2 Lentiviral Activation Particles (h) - sc-408390-LAC from Santa Cruz Biotechnology
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ZP2 Lentiviral Activation Particles (h2) - sc-408390-LAC-2 from Santa Cruz Biotechnology
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ZP2 siRNA (h) - sc-44886 from Santa Cruz Biotechnology
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ZP2 shRNA Plasmid (h) - sc-44886-SH from Santa Cruz Biotechnology
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ZP2 shRNA (h) Lentiviral Particles - sc-44886-V from Santa Cruz Biotechnology
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ZP2 RNAi - H00007783-R02 from Novus Biologicals
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MISSION® esiRNA - EHU005461 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN23788 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23788 from Sigma-Aldrich
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ZP2 siRNA (Human) - CRH5271 from Cohesion Biosciences
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ZP2 - MBS8230471 from MyBioSource
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ZP2 shRNA Plasmid (Human) - CHH5271 from Cohesion Biosciences
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