COX4I2

Gene Symbol COX4I2
Entrez Gene 84701
Alt Symbol COX4, COX4-2, COX4B, COX4L2, COXIV-2, dJ857M17.2
Species Human
Gene Type protein-coding
Description cytochrome c oxidase subunit IV isoform 2 (lung)
Other Description COX IV-2|cytochrome c oxidase subunit 4 isoform 2, mitochondrial|cytochrome c oxidase subunit IV-like 2
Swissprots Q9H0Z4 Q6GTF4 Q96KJ9
Accessions EAW76431 Q96KJ9 AF257180 AAK49333 BC057779 AAH57779 HE647859 CCF23107 XM_005260579 XP_005260636 XM_005260580 XP_005260637 XM_005260581 XP_005260638 XM_011529086 XP_011527388 NM_032609 NP_115998
Function This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.
Subcellular Location Mitochondrion inner membrane.
Tissue Specificity Highly expressed in lung.
Top Pathways Alzheimer's disease, Huntington's disease, Cardiac muscle contraction, Non-alcoholic fatty liver disease (NAFLD), Oxidative phosphorylation

COX4I2 (RR3) - sc-100522 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
COX4I2 (RR3): sc-100522. Immunoperoxidase staining of formalin-fixed, paraffin-embedded human salivary gland tissue showing cytoplasmic localization.

COX4I2 (Y-16) - sc-86386 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-COXIV Isoform 2 antibody - ab70112 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab70112 at 1/500 dilution staining COXIV Isoform 2 in COS7 cells by Immunofluorescence, in the absence or presence of the immunising peptide.

Anti-COXIV Isoform 2 antibody - ab190168 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labeling COXIV Isoform 2 with ab190168 at 20 µg/ml.

Anti-COXIV Isoform 2 antibody - ab199693 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of COS7 cells labeling COXIV Isoform 2 with ab199693 at 1/100 dilution.

Anti-COX4I2 Antibody (aa39-171, clone 1D4B) - LS-C189795 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1D4B

Anti-COX4I2 Antibody (clone 1F2) - LS-C105191 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 1F2
Western blot of COX4I2 expression in transfected 293T cell line by COX4I2 monoclonal antibody (M01), clone 1F2.

Anti-COX4I2 Antibody - LS-C311059 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-COX4I2 Antibody (C-Terminus) - LS-C108119 from LifeSpan Bioscience

Host Goat
Clonality Polyclonal
COX4I2 antibody (1 ug/ml) staining of Human Skeletal Muscle lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-COX4I2 Antibody (aa21-105, Azide-free) - LS-C330396 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-COX4I2 Antibody (aa31-80) IHC-plus™ - LS-B9672 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-COX4I2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9672 concentration 20 ug/ml.

COX IV Isoform 2 Antibody (1F2) - H00084701-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F2
Western Blot: COX IV Isoform 2 Antibody (1F2) [H00084701-M01] - Analysis of COX4I2 expression in transfected 293T cell line by COX4I2 monoclonal antibody (M01), clone 1F2.Lane 1: COX4I2 transfected lysate(20 KDa).Lane 2: Non-transfected lysate.

COX IV Isoform 2 Antibody - NBP1-88058 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: COX IV Isoform 2 Antibody [NBP1-88058] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Negative control (vector only transfected HEK293T lysate)<br/>Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY410005)

COX IV Isoform 2 Antibody - NBP1-44068 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

COX IV Isoform 2 Antibody - H00084701-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: COX IV Isoform 2 Antibody [H00084701-D01P] - analysis of COX4I2 expression in transfected 293T cell line by COX4I2 MaxPab rabbit polyclonal antibody. Lane 1: COX4I2 transfected lysate (20.00 KDa). Lane 2: Non-transfected lysate.

Anti-COX4I2 (C-terminal) antibody produced in goat - SAB2501168 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-COX4I2 (C-terminal): <B>Cat. No. SAB2501168</B>: (1 μg/mL) staining of Human Skeletal Muscle lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Monoclonal Anti-COX4I2 antibody produced in mouse - WH0084701M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F2
<B>Immunoblotting</B><BR/>Monoclonal Anti-COX4I2, <B>Cat. No. WH0084701M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~35.35 kDa using immunogen protein lysate.

Anti-COX4I2 antibody produced in rabbit - SAB1401897 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-COX4I2, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401897</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~20.00 kDa using COX4I2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-COX4I2 antibody produced in rabbit - HPA029307 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-COX4I2: <B>Cat. No. HPA029307</B>: Immunohistochemical staining of human testis shows moderate cytoplasmic positivity in cells of seminiferus ducts and strong staining in endothelial smooth muscle.

Anti-COX42 antibody produced in rabbit - SAB4503384 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-COX42: <B>Cat. No. SAB4503384</B>: Immunofluorescence of COS7 cells using Anti-COX42 antibody. Cells on the left were treated with the Anti-COX42 antibody. Cells on the right (negative control) were treated with both Anti-COX42 antibody and the synthesized immunogen peptide.

COX4I2-Antibody-monoclonal-M01 - AT1598a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1F2
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (34.98 KDa) .

COX42-Antibody - AP50659 from Abgent, a WuXi AppTec company

Prices $295.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysate from human skeletal muscle tissue lysate,using COX42 Antibody(AP50659). AP50659 was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysate at 35ug.

COX4I2 / COX4I1 antibody, C-term - GTX47597 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-COX4I2 / COX4I1 antibody, C-term used in Western blot. GTX47597

Human/Mouse COX4 Antibody - MAB6980 from R&D Systems

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clone 673803
Detection of Human and Mouse COX4 by Western Blot. Western blot shows lysates of A431 human epithelial carcinoma cell line, HepG2 human hepatocellular carcinoma cell line, and NIH-3T3 mouse embryonic fibroblast cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human COX4 Monoclonal Antibody (Catalog # MAB6980) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007 ). For addtional reference, recombinant human COX4-I1 (5 ng/lane) and recombinant human COX4-I2 (2.5 ng/lane) were included. A specific band was detected for COX4 at approximately 18 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 2 .

Human/Mouse COX4 MAb (Clone 673803), Mouse IgG2B - MAB6980-SP from R&D Systems

Host Mouse
Clonality Monoclonal
Clone 673803
Detection of Human and Mouse COX4 by Western Blot. Western blot shows lysates of A431 human epithelial carcinoma cell line, HepG2 human hepatocellular carcinoma cell line, and NIH‑3T3 mouse embryonic fibroblast cell line. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human COX4 Monoclonal Antibody (Catalog # MAB6980) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). For addtional reference,  recombinant human COX4-I1 (5 ng/lane) and recombinant human COX4-I2 (2.5 ng/lane) were included. A specific band was detected for COX4 at approximately 18 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 2.
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