Gene Symbol |
RABGAP1
|
Entrez Gene |
23637
|
Alt Symbol |
GAPCENA, TBC1D11
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
RAB GTPase activating protein 1
|
Other Description |
GAP and centrosome-associated protein|Rab6 GTPase activating protein, GAPCenA|TBC1 domain family, member 11|rab GTPase-activating protein 1|rab6 GTPase activating protein (GAP and centrosome-associated)|rab6 GTPase-activating protein GAPCenA
|
Swissprots |
B9A6L2 Q9Y3P9 Q9P0E2 Q6ZMY1 Q9UG67 Q9HA28 Q05CW2
|
Accessions |
EAW87554 EAW87555 EAW87556 EAW87557 Q9Y3P9 AA948302 AB449897 BAH16640 AF088073 AF161357 AAF28917 AJ011679 CAB40267 AK022408 AK131449 BAD18594 AK294531 BAH11800 AL050195 CAB43313 BC020609 AAH20609 BC054492 AAH54492 BG622097 XM_005251868 XP_005251925 XM_011518440 XP_011516742 XM_011518441 XP_011516743 XM_011518442 XP_011516744 XM_011518443 XP_011516745 XM_011518444 XP_011516746 XM_011518445 XP_011516747 XR_929742 NM_012197 NP_036329
|
Function |
May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase- anaphase transition. {ECO:0000269|PubMed:10202141, ECO:0000269|PubMed:16395330}.
|
Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:10202141}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:10202141}. Note=Predominantly cytosolic but also associated with the centrosome. {ECO:0000269|PubMed:10202141}.
|