Gene Symbol | RABGAP1 |
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Entrez Gene | 23637 |
Alt Symbol | GAPCENA, TBC1D11 |
Species | Human |
Gene Type | protein-coding |
Description | RAB GTPase activating protein 1 |
Other Description | GAP and centrosome-associated protein|Rab6 GTPase activating protein, GAPCenA|TBC1 domain family, member 11|rab GTPase-activating protein 1|rab6 GTPase activating protein (GAP and centrosome-associated)|rab6 GTPase-activating protein GAPCenA |
Swissprots | B9A6L2 Q9Y3P9 Q9P0E2 Q6ZMY1 Q9UG67 Q9HA28 Q05CW2 |
Accessions | EAW87554 EAW87555 EAW87556 EAW87557 Q9Y3P9 AA948302 AB449897 BAH16640 AF088073 AF161357 AAF28917 AJ011679 CAB40267 AK022408 AK131449 BAD18594 AK294531 BAH11800 AL050195 CAB43313 BC020609 AAH20609 BC054492 AAH54492 BG622097 XM_005251868 XP_005251925 XM_011518440 XP_011516742 XM_011518441 XP_011516743 XM_011518442 XP_011516744 XM_011518443 XP_011516745 XM_011518444 XP_011516746 XM_011518445 XP_011516747 XR_929742 NM_012197 NP_036329 |
Function | May act as a GTPase-activating protein of RAB6A. May play a role in microtubule nucleation by centrosome. May participate in a RAB6A-mediated pathway involved in the metaphase- anaphase transition. {ECO:0000269|PubMed:10202141, ECO:0000269|PubMed:16395330}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:10202141}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:10202141}. Note=Predominantly cytosolic but also associated with the centrosome. {ECO:0000269|PubMed:10202141}. |
Rab GAP1 CRISPR/Cas9 KO Plasmid (h) - sc-406952 from Santa Cruz Biotechnology
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Rab GAP1 HDR Plasmid (h) - sc-406952-HDR from Santa Cruz Biotechnology
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Rab GAP1 Double Nickase Plasmid (h) - sc-406952-NIC from Santa Cruz Biotechnology
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Rab GAP1 Double Nickase Plasmid (h2) - sc-406952-NIC-2 from Santa Cruz Biotechnology
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Rab GAP1 CRISPR Activation Plasmid (h) - sc-406952-ACT from Santa Cruz Biotechnology
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Rab GAP1 CRISPR Activation Plasmid (h2) - sc-406952-ACT-2 from Santa Cruz Biotechnology
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Rab GAP1 Lentiviral Activation Particles (h) - sc-406952-LAC from Santa Cruz Biotechnology
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Rab GAP1 Lentiviral Activation Particles (h2) - sc-406952-LAC-2 from Santa Cruz Biotechnology
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Rab GAP1 siRNA (h) - sc-92500 from Santa Cruz Biotechnology
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Rab GAP1 shRNA Plasmid (h) - sc-92500-SH from Santa Cruz Biotechnology
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Rab GAP1 shRNA (h) Lentiviral Particles - sc-92500-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU089171 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17876 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17876 from Sigma-Aldrich
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RABGAP1 siRNA (Human) - CRH8413 from Cohesion Biosciences
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RABGAP1 RNAi - H00023637-R01 from Novus Biologicals
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RABGAP1 - MBS8240707 from MyBioSource
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shRNA set against Human RABGAP1 (NM_012197.3) - SHH388704 from Creative biogene
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shRNA set against Human RABGAP1(NM_012197.3) - SHR160320 from Creative biogene
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Human RABGAP1 siRNA - orb268915 from Biorbyt
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RABGAP1 shRNA Plasmid (Human) - CHH8413 from Cohesion Biosciences
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RABGAP1 miRNA 3'UTR clone - MiUTR1H-08581 from Creative biogene
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