| Gene Symbol |
IGFBP1
|
| Entrez Gene |
3484
|
| Alt Symbol |
AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
insulin-like growth factor binding protein 1
|
| Other Description |
IBP-1|IGF-binding protein 1|IGFBP-1|alpha-pregnancy-associated endometrial globulin|amniotic fluid binding protein|binding protein-25|binding protein-26|binding protein-28|growth hormone independent-binding protein|insulin-like growth factor-binding protein 1|placental protein 12
|
| Swissprots |
A4D2F4 P08833 D3DVL9 Q8IYP5
|
| Accessions |
AAA52783 AAA52784 AAA52785 AAQ96599 AAS07553 CAJ21549 CBH19324 CBX53887 EAL23800 EAW61030 EAW61031 P08833 AF042356 AK314925 BAG37433 AV695706 BC035263 AAH35263 BC057806 AAH57806 BT019685 AAV38491 CA429917 FJ795026 ACO37638 M20841 AAA52540 M31145 AAA52542 X12385 CAA30942 X13405 CAA31771 X15002 CAA33110 Y00856 CAA68770 NM_000596 NP_000587 NM_001013029
|
| Function |
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Promotes cell migration. {ECO:0000269|PubMed:15972819}.
|
| Subcellular Location |
Secreted.
|
![Western Blot: IGFBP1 Overexpression Lysate (Adult Normal) [NBL1-11873] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for IGFBP1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11982_IGFBP1%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-11873-img0002.jpg)