EIF5A2

Gene Symbol EIF5A2
Entrez Gene 56648
Alt Symbol EIF-5A2, eIF5AII
Species Human
Gene Type protein-coding
Description eukaryotic translation initiation factor 5A2
Other Description eIF-5A-2|eukaryotic initiation factor 5A|eukaryotic translation initiation factor 5A-2
Swissprots Q9GZV4 B2R4V5
Accessions AAG23176 EAW78501 Q9GZV4 AK311962 BAG34902 AY205258 AAO18676 AY205259 AAO18677 AY205260 AAO18678 AY205261 AAO18679 BC034420 BC036072 AAH36072 DQ890965 ABM81891 DQ894138 ABM85064 NM_020390 NP_065123
Function mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Nucleus, nuclear pore complex {ECO:0000250}. Note=Hypusine modification promotes the nuclear export and cytoplasmic localization and there was a dynamic shift in the localization from predominantly cytoplasmic to primarily nuclear under apoptotic inducing conditions. {ECO:0000250}.
Tissue Specificity Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells. {ECO:0000269|PubMed:11161802, ECO:0000269|PubMed:16519677}.

eIF5A2 (C-15) - sc-99392 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-eIF5A2 antibody - ab57421 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57421 eIF5A2 antibody at 1ug/ml.

Anti-eIF5A2 antibody - ab97314 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-eIF5A2 antibody (ab97314) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : H1299 whole cell lysateLane 4 : HeLaS3 whole cell lysateLane 5 : HepG2 whole cell lysateLane 6 : Molt-4 whole cell lysateLane 7 : Raji whole cell lysateLysates/proteins at 30 µg per lane.

Anti-eIF5A2 antibody - ab135851 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-eIF5A2 antibody (ab135851) at 1/500 dilution + HuvEc cell extracts at 10 µg

Anti-eIF5A2 antibody [EPR7411] - ab126735 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7411
Overlay histogram showing HeLa cells stained with ab126735 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab126735, 1/100 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H+L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter.

Anti-eIF5A2 antibody [EPR7411] - ab150403 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7411
All lanes : Anti-eIF5A2 antibody [EPR7411] (ab150403) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : SW480 cell lysateLane 3 : RAW264.7 cell lysateLane 4 : NIH 3T3 cell lysateLane 5 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-eIF5A2 antibody [EPR7412] - ab150439 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7412
All lanes : Anti-eIF5A2 antibody [EPR7412] (ab150439) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : HeLa cell lysateLane 3 : 293T cell lysateLane 4 : Raji cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP labelled antibody at 1/2000 dilution

Anti-eIF5A2 antibody [EPR7412] - ab126733 from Abcam

Prices $313.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7412
All lanes : Anti-eIF5A2 antibody [EPR7412] (ab126733) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : Caco 2 cell lysateLysates/proteins at 10 µg per lane.SecondaryGoat-anti-rabbit HRP at 1/2000 dilutiondeveloped using the ECL technique

Anti-EIF5A2 Antibody (clone 6G7) - LS-C174144 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 6G7
IHC of paraffin-embedded Human pancreas tissue using anti-EIF5A2 mouse monoclonal antibody.

Anti-EIF5A2 Antibody - LS-C6735 from LifeSpan Bioscience

Prices $325.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-EIF5A2 Antibody (aa108-122) - LS-C40660 from LifeSpan Bioscience

Prices $275.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-EIF5A2 Antibody (N-Terminus) - LS-C112053 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EIF5A2 antibody LS-C112053 Western blot of Fetal Liver lysate.

Anti-EIF5A2 Antibody (aa93-122, APC) - LS-C234904 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF5A2 Antibody (aa93-122, AP) - LS-C234903 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF5A2 Antibody (aa93-122, Biotin) - LS-C234905 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF5A2 Antibody (Internal, clone EPR7411) - LS-C152356 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7411
IHC of paraffin-embedded human ovarian carcinoma using anti-eIF5A2 antibody.

Anti-EIF5A2 Antibody (Tyr127) - LS-C178246 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of eIF5A2 (Y127) pAb in extracts from HUVEC cells.

Anti-EIF5A2 Antibody (Internal, clone EPR7412) - LS-C152387 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR7412
IHC of paraffin-embedded human ovarian carcinoma tissue using anti-eIF5A2 antibody.

Anti-EIF5A2 Antibody (aa93-122, FITC) - LS-C234906 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF5A2 Antibody (aa93-122, PE) - LS-C234910 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF5A2 Antibody (aa139-153) IHC-plus™ - LS-B281 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-eIF5A2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B281 concentration 5 ug/ml.

Anti-EIF5A2 Antibody (clone 2E9) - LS-C174136 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2E9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY EIF5A2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-EIF5A2.

Anti-EIF5A2 Antibody (aa93-122, Azide-free, HRP) - LS-C249899 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-EIF5A2 Antibody (aa93-122) - LS-C167715 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
EIF5A2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human ovarian carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-EIF5A2 Antibody (aa92-122) - LS-C321083 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more