| Gene Symbol |
DOLK
|
| Entrez Gene |
22845
|
| Alt Symbol |
CDG1M, DK, DK1, SEC59, TMEM15
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
dolichol kinase
|
| Other Description |
SEC59 homolog|dolichol kinase 1|transmembrane protein 15
|
| Swissprots |
Q9UPQ8 Q5SRE6
|
| Accessions |
EAW87849 Q9UPQ8 AB029017 BAA83046 AK225402 AK300180 BAG61959 AY358759 AAQ89119 BC035556 AAH35556 BF056649 JF432695 ADZ15912 NM_014908 NP_055723
|
| Function |
Involved in the synthesis of the sugar donor Dol-P-Man which is required in the synthesis of N-linked and O-linked oligosaccharides and for that of GPI anchors. {ECO:0000250}.
|
| Subcellular Location |
Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Ubiquitous.
|
| Top Pathways |
N-Glycan biosynthesis
|