| Gene Symbol |
RAP1GAP
|
| Entrez Gene |
5909
|
| Alt Symbol |
RAP1GA1, RAP1GAP1, RAP1GAPII, RAPGAP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
RAP1 GTPase activating protein
|
| Other Description |
rap1 GTPase-activating protein 1
|
| Swissprots |
O75062 Q9UQ51 Q5T3T4 P47736 J3QSS6 Q5T3S9 Q7Z5S8
|
| Accessions |
EAW94979 EAW94980 EAW94981 EAW94982 EAW94983 EAW94984 EAW94985 EAW94986 P47736 AB003930 BAA83674 AB007943 BAA32319 AI827348 BC035030 AAH35030 BC054490 AAH54490 BM739021 BP200029 BP283134 CV574545 EU831750 ACE87268 EU831826 ACE86585 LN607839 CEF49526 M64788 AAA60252 XM_005245955 XP_005246012 XM_006710804 XP_006710867 XM_006710805 XP_006710868 XR_946725 XR_946726 XR_946727 XR_946728 XR_946729 XR_946730 XR_946731 XR_946732 XR_946733 NM_001145657 NP_001139129 NM_001145658 NP_001139130 NM_002885 NP_002876
|
| Function |
GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. {ECO:0000269|PubMed:15141215}.
|
| Subcellular Location |
Golgi apparatus membrane; Peripheral membrane protein.
|
| Tissue Specificity |
Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues. {ECO:0000269|PubMed:9346962}.
|
| Top Pathways |
Rap1 signaling pathway
|