Gene Symbol | RAP1GAP |
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Entrez Gene | 5909 |
Alt Symbol | RAP1GA1, RAP1GAP1, RAP1GAPII, RAPGAP |
Species | Human |
Gene Type | protein-coding |
Description | RAP1 GTPase activating protein |
Other Description | rap1 GTPase-activating protein 1 |
Swissprots | O75062 Q9UQ51 Q5T3T4 P47736 J3QSS6 Q5T3S9 Q7Z5S8 |
Accessions | EAW94979 EAW94980 EAW94981 EAW94982 EAW94983 EAW94984 EAW94985 EAW94986 P47736 AB003930 BAA83674 AB007943 BAA32319 AI827348 BC035030 AAH35030 BC054490 AAH54490 BM739021 BP200029 BP283134 CV574545 EU831750 ACE87268 EU831826 ACE86585 LN607839 CEF49526 M64788 AAA60252 XM_005245955 XP_005246012 XM_006710804 XP_006710867 XM_006710805 XP_006710868 XR_946725 XR_946726 XR_946727 XR_946728 XR_946729 XR_946730 XR_946731 XR_946732 XR_946733 NM_001145657 NP_001139129 NM_001145658 NP_001139130 NM_002885 NP_002876 |
Function | GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state. {ECO:0000269|PubMed:15141215}. |
Subcellular Location | Golgi apparatus membrane; Peripheral membrane protein. |
Tissue Specificity | Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues. {ECO:0000269|PubMed:9346962}. |
Top Pathways | Rap1 signaling pathway |
RAP1GAP peptide - ab139973 from Abcam
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RAP1GAP Antibody Blocking Peptide - LS-E20529 from LifeSpan Bioscience
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RAP1GAP Antibody Blocking Peptide - LS-E20530 from LifeSpan Bioscience
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Recombinant Human RAP1GAP Protein - H00005909-P01 from Novus Biologicals
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RAP1GAP peptide - orb217852 from Biorbyt
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RAP1GAP Blocking Peptide - 33R-9380 from Fitzgerald
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RAP1GAP Blocking Peptide - 33R-3948 from Fitzgerald
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RAP1GAP Blocking Peptide - abx063183 from Abbexa
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RAP1GAP - H00005909-P01-10 from Acris Antibodies
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RAP1GAP - H00005909-P01-25 from Acris Antibodies
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RAP1GAP fusion protein - ag5469 from Proteintech Group
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RAP1GAP fusion protein - Ag5576 from Proteintech Group
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Recombinant Human RAP1 GTPase Activating Protein - RAP1GAP-1129H from Creative Biomart
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Recombinant Human RAP1GAP, His-tagged - RAP1GAP-30503TH from Creative Biomart
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RAP1GAP Blocking Peptide - CBP1989 from Cohesion Biosciences
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RAP1GAP Peptide - BS5883P from Bioworld Technology
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Recombinant Human Rap1 GTPase-activating protein 1(RAP1GAP) - CSB-YP019324HU CSB-EP019324HU CSB-BP019324HU CSB-MP019324HU from Cusabio
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RAP1GAP (transcript variant 3) - TP308271 from Acris Antibodies
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Recombinant Human RAP1GAP - CSI13789 from Cell Science
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RAP1GAP Recombinant Protein Antigen - NBP1-83002PEP from Novus Biologicals
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RAP1GAP-Blocking-Peptide-N-Term - BP21784a from Abgent, a WuXi AppTec company
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RAP1GAP Peptide, Human - M34GP12961H from Creative Peptides
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Rap1 GTPase-activating protein 1 (RAP1GAP), Recombinant Protein - MBS952302 from MyBioSource
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