| Gene Symbol | H2AFZ |
|---|---|
| Entrez Gene | 287016 |
| Alt Symbol | - |
| Species | Bovine |
| Gene Type | protein-coding |
| Description | H2A histone family, member Z |
| Other Description | H2A/z|histone H2A.Z |
| Swissprots | P0C0S4 Q32L66 |
| Accessions | DAA28849 P0C0S4 BC109743 AAI09744 M37585 AAA30566 X52318 CAA36554 XM_010805947 XP_010804249 NM_174809 NP_777234 |
| Function | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus. Chromosome. |
| Top Pathways | Systemic lupus erythematosus, Alcoholism |
H2A histone family, member Z, ELISA Kit - MBS9327804 from MyBioSource
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Bovine H2AFZ ELISA Kit - E085114 from Biobool
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