Gene Symbol | H2AFZ |
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Entrez Gene | 287016 |
Alt Symbol | - |
Species | Bovine |
Gene Type | protein-coding |
Description | H2A histone family, member Z |
Other Description | H2A/z|histone H2A.Z |
Swissprots | P0C0S4 Q32L66 |
Accessions | DAA28849 P0C0S4 BC109743 AAI09744 M37585 AAA30566 X52318 CAA36554 XM_010805947 XP_010804249 NM_174809 NP_777234 |
Function | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Alcoholism |
Anti-Histone H2A.Z antibody - ab118305 from Abcam
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Anti-Histone H2A.Z antibody [4A4] - ab80150 from Abcam
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Anti-Histone H2A.Z antibody [8H8] - ab80153 from Abcam
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Anti-Histone H2A.Z antibody [IC10] - ab4462 from Abcam
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Anti-Histone H2A.Z antibody - ChIP Grade - ab4174 from Abcam
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Anti-Histone H2A.Z antibody - N-terminal - ab175552 from Abcam
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Histone Core Complex (H2A, H2B, H3, H4) Antibody - 30198-05111 from AssayPro
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Histone Core Complex (H2A, H2B, H3, H4) Antibody (Biotin Conjugate) - 30198-05121 from AssayPro
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Histone Core Complex (H2A, H2B, H3, H4) Antibody (FITC Conjugate) - 30198-05141 from AssayPro
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Histone Core Complex (H2A, H2B, H3, H4) Antibody (RPE Conjugate) - 30198-05151 from AssayPro
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Histone Core Complex (H2A, H2B, H3, H4) Antibody (APC Conjugate) - 30198-05161 from AssayPro
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Histone Core Complex (H2A, H2B, H3, H4) Antibody (PerCP Conjugate) - 30198-05171 from AssayPro
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