| Gene Symbol |
CNOT11
|
| Entrez Gene |
55571
|
| Alt Symbol |
C2orf29, C40
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
CCR4-NOT transcription complex, subunit 11
|
| Other Description |
CCR4-NOT transcription complex subunit 11|UPF0760 protein C2orf29
|
| Swissprots |
Q6P2M9 Q9UKZ1 Q8N681
|
| Accessions |
AAY15088 EAX01821 Q9UKZ1 AF103798 AAF02418 AK024221 BAG51272 BC018664 AAH18664 BC064421 AAH64421 BM923954 BX394182 NM_017546 NP_060016
|
| Function |
Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function.
|
| Subcellular Location |
Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}.
|
![Western Blot: C2orf29 Overexpression Lysate (Adult Normal) [NBL1-08408] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C2orf29.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/11433_C2orf29%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBL1-08408-img0002.jpg)