Gene Symbol | CNOT11 |
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Entrez Gene | 55571 |
Alt Symbol | C2orf29, C40 |
Species | Human |
Gene Type | protein-coding |
Description | CCR4-NOT transcription complex, subunit 11 |
Other Description | CCR4-NOT transcription complex subunit 11|UPF0760 protein C2orf29 |
Swissprots | Q6P2M9 Q9UKZ1 Q8N681 |
Accessions | AAY15088 EAX01821 Q9UKZ1 AF103798 AAF02418 AK024221 BAG51272 BC018664 AAH18664 BC064421 AAH64421 BM923954 BX394182 NM_017546 NP_060016 |
Function | Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Is required for the association of CNOT10 with the CCR4-NOT complex. Seems not to be required for complex deadenylase function. |
Subcellular Location | Cytoplasm {ECO:0000305}. Nucleus {ECO:0000305}. |
C2orf29 CRISPR/Cas9 KO Plasmid (h) - sc-412548 from Santa Cruz Biotechnology
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C2orf29 HDR Plasmid (h) - sc-412548-HDR from Santa Cruz Biotechnology
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C2orf29 Double Nickase Plasmid (h) - sc-412548-NIC from Santa Cruz Biotechnology
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C2orf29 Double Nickase Plasmid (h2) - sc-412548-NIC-2 from Santa Cruz Biotechnology
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C2orf29 CRISPR Activation Plasmid (h) - sc-412548-ACT from Santa Cruz Biotechnology
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C2orf29 CRISPR Activation Plasmid (h2) - sc-412548-ACT-2 from Santa Cruz Biotechnology
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C2orf29 Lentiviral Activation Particles (h) - sc-412548-LAC from Santa Cruz Biotechnology
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C2orf29 Lentiviral Activation Particles (h2) - sc-412548-LAC-2 from Santa Cruz Biotechnology
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C2orf29 siRNA (h) - sc-94334 from Santa Cruz Biotechnology
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C2orf29 shRNA Plasmid (h) - sc-94334-SH from Santa Cruz Biotechnology
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C2orf29 shRNA (h) Lentiviral Particles - sc-94334-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU027871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4821 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4821 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07275 from Sigma-Aldrich
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CNOT11 siRNA (Human) - CRJ0745 from Cohesion Biosciences
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CNOT11 - MBS829199 from MyBioSource
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Human CNOT11 siRNA - orb271246 from Biorbyt
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CNOT11 shRNA Plasmid (Human) - CHJ0745 from Cohesion Biosciences
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C2ORF29 miRNA 3'UTR clone - MiUTR3H-14107 from Creative biogene
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