NT5C2

Gene Symbol NT5C2
Entrez Gene 22978
Alt Symbol GMP, NT5B, PNT5, SPG45, SPG65, cN-II
Species Human
Gene Type protein-coding
Description 5'-nucleotidase, cytosolic II
Other Description 5'-nucleotidase (purine), cytosolic type B|IMP-specific 5'-NT|cytosolic 5'-nucleotidase II|cytosolic purine 5'-nucleotidase|purine 5' nucleotidase
Swissprots D3DR91 Q5JUV5 P49902 B7Z382
Accessions EAW49656 EAW49657 P49902 AK127670 BAG54547 AK291667 BAF84356 AK295593 BAH12118 AK312517 BC001595 AAH01595 BU618027 BX648078 D38524 BAA07529 DA879821 DB169780 DQ892526 ABM83452 DQ895738 ABM86664 XM_005269632 XP_005269689 XM_005269633 XP_005269690 XM_005269634 XP_005269691 XM_005269635 XP_005269692 XM_005269636 XP_005269693 XM_005269637 XP_005269694 XM_005269638 XP_005269695 XM_005269639 XP_005269696 XM_005269640 XP_005269697 XM_005269641 XP_005269698 XM_005269642 XP_005269699 XM_005269643 XP_005269700 XM_005269644 XP_005269701 XM_005269645 XP_005269702 XM_005269646 XP_005269703 XM_006717721 XP_006717784 XM_006717722 XP_006717785 XM_006717723 XP_006717786 XM_006717724 XP_006717787 XM_011539534 XP_011537836 XM_011539535 XP_011537837 XM_011539536 XP_011537838 XM_011539537 XP_011537839 NM_001134373 NP_001127845 NM_012229 NP_036361
Function May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.
Subcellular Location Cytoplasm.
Top Pathways Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism