| Gene Symbol |
NT5C2
|
| Entrez Gene |
22978
|
| Alt Symbol |
GMP, NT5B, PNT5, SPG45, SPG65, cN-II
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
5'-nucleotidase, cytosolic II
|
| Other Description |
5'-nucleotidase (purine), cytosolic type B|IMP-specific 5'-NT|cytosolic 5'-nucleotidase II|cytosolic purine 5'-nucleotidase|purine 5' nucleotidase
|
| Swissprots |
D3DR91 Q5JUV5 P49902 B7Z382
|
| Accessions |
EAW49656 EAW49657 P49902 AK127670 BAG54547 AK291667 BAF84356 AK295593 BAH12118 AK312517 BC001595 AAH01595 BU618027 BX648078 D38524 BAA07529 DA879821 DB169780 DQ892526 ABM83452 DQ895738 ABM86664 XM_005269632 XP_005269689 XM_005269633 XP_005269690 XM_005269634 XP_005269691 XM_005269635 XP_005269692 XM_005269636 XP_005269693 XM_005269637 XP_005269694 XM_005269638 XP_005269695 XM_005269639 XP_005269696 XM_005269640 XP_005269697 XM_005269641 XP_005269698 XM_005269642 XP_005269699 XM_005269643 XP_005269700 XM_005269644 XP_005269701 XM_005269645 XP_005269702 XM_005269646 XP_005269703 XM_006717721 XP_006717784 XM_006717722 XP_006717785 XM_006717723 XP_006717786 XM_006717724 XP_006717787 XM_011539534 XP_011537836 XM_011539535 XP_011537837 XM_011539536 XP_011537838 XM_011539537 XP_011537839 NM_001134373 NP_001127845 NM_012229 NP_036361
|
| Function |
May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides.
|
| Subcellular Location |
Cytoplasm.
|
| Top Pathways |
Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism
|
![Western Blot: NT5C2 Overexpression Lysate (Adult Normal) [NBP2-09536] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NT5C2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6185_NT5C2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-09536-img0001.jpg)