Gene Symbol | NT5C2 |
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Entrez Gene | 22978 |
Alt Symbol | GMP, NT5B, PNT5, SPG45, SPG65, cN-II |
Species | Human |
Gene Type | protein-coding |
Description | 5'-nucleotidase, cytosolic II |
Other Description | 5'-nucleotidase (purine), cytosolic type B|IMP-specific 5'-NT|cytosolic 5'-nucleotidase II|cytosolic purine 5'-nucleotidase|purine 5' nucleotidase |
Swissprots | D3DR91 Q5JUV5 P49902 B7Z382 |
Accessions | EAW49656 EAW49657 P49902 AK127670 BAG54547 AK291667 BAF84356 AK295593 BAH12118 AK312517 BC001595 AAH01595 BU618027 BX648078 D38524 BAA07529 DA879821 DB169780 DQ892526 ABM83452 DQ895738 ABM86664 XM_005269632 XP_005269689 XM_005269633 XP_005269690 XM_005269634 XP_005269691 XM_005269635 XP_005269692 XM_005269636 XP_005269693 XM_005269637 XP_005269694 XM_005269638 XP_005269695 XM_005269639 XP_005269696 XM_005269640 XP_005269697 XM_005269641 XP_005269698 XM_005269642 XP_005269699 XM_005269643 XP_005269700 XM_005269644 XP_005269701 XM_005269645 XP_005269702 XM_005269646 XP_005269703 XM_006717721 XP_006717784 XM_006717722 XP_006717785 XM_006717723 XP_006717786 XM_006717724 XP_006717787 XM_011539534 XP_011537836 XM_011539535 XP_011537837 XM_011539536 XP_011537838 XM_011539537 XP_011537839 NM_001134373 NP_001127845 NM_012229 NP_036361 |
Function | May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides. |
Subcellular Location | Cytoplasm. |
Top Pathways | Purine metabolism, Nicotinate and nicotinamide metabolism, Pyrimidine metabolism |
NT5C2 CRISPR/Cas9 KO Plasmid (h) - sc-408511 from Santa Cruz Biotechnology
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NT5C2 HDR Plasmid (h) - sc-408511-HDR from Santa Cruz Biotechnology
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NT5C2 Double Nickase Plasmid (h) - sc-408511-NIC from Santa Cruz Biotechnology
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NT5C2 Double Nickase Plasmid (h2) - sc-408511-NIC-2 from Santa Cruz Biotechnology
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NT5C2 CRISPR Activation Plasmid (h) - sc-408511-ACT from Santa Cruz Biotechnology
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NT5C2 CRISPR Activation Plasmid (h2) - sc-408511-ACT-2 from Santa Cruz Biotechnology
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NT5C2 Lentiviral Activation Particles (h) - sc-408511-LAC from Santa Cruz Biotechnology
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NT5C2 Lentiviral Activation Particles (h2) - sc-408511-LAC-2 from Santa Cruz Biotechnology
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NT5C2 siRNA (h) - sc-90370 from Santa Cruz Biotechnology
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NT5C2 shRNA Plasmid (h) - sc-90370-SH from Santa Cruz Biotechnology
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NT5C2 shRNA (h) Lentiviral Particles - sc-90370-V from Santa Cruz Biotechnology
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NT5C2 RNAi - H00022978-R01 from Novus Biologicals
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MISSION® esiRNA - EHU011761 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0363 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0361 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0362 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN15549 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15549 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09732 from Sigma-Aldrich
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NT5C2 siRNA (Human) - CRH7902 from Cohesion Biosciences
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shRNA set against Human NT5C2 (NM_012229.4) - SHH355540 from Creative biogene
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Human NT5C2 siRNA - orb268404 from Biorbyt
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NT5C2 shRNA Plasmid (Human) - CHH7902 from Cohesion Biosciences
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NT5C2 miRNA 3'UTR clone - MiUTR4H-TG06152 from Creative biogene
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