| Gene Symbol |
CFHR1
|
| Entrez Gene |
3078
|
| Alt Symbol |
CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, H36-1, H36-2, HFL1, HFL2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
complement factor H-related 1
|
| Other Description |
FHR-1|H factor (complement)-like 1|H factor (complement)-like 2|H-factor-like 1|H36|complement factor H-related 1 pseudogene|complement factor H-related protein 1|h factor-like protein 1
|
| Swissprots |
Q03591 Q3B774 Q9UJ17 A8K465
|
| Accessions |
CBN73473 Q03591 AI075816 AK290830 BAF83519 AK311681 BC016755 AAH16755 BC107771 AAI07772 BG568702 DQ892762 ABM83688 DQ896007 ABM86991 M65292 AAA35946 M65293 AAA35947 X56209 CAA39666 X56210 CAA39667 XM_006711284 XP_006711347 XM_011509457 XP_011507759 NM_002113 NP_002104
|
| Function |
Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. {ECO:0000269|PubMed:23487775}.
|
| Subcellular Location |
Secreted.
|
| Tissue Specificity |
Expressed by the liver and secreted in plasma.
|