TYK2

Gene Symbol	TYK2
Entrez Gene	7297
Alt Symbol	IMD35, JTK1
Species	Human
Gene Type	protein-coding
Description	tyrosine kinase 2
Other Description	non-receptor tyrosine-protein kinase TYK2
Swissprots	Q6QB10 Q96CH0 P29597
Accessions	AAS37680 EAW84099 EAW84100 P29597 AK222672 BAD96392 AK303627 BAG64635 AK308360 AK308379 BC014243 AAH14243 CR995139 DA864169 DQ892692 ABM83618 DQ895955 ABM86881 X54637 CAA38449 XM_011528245 XP_011526547 XM_011528246 XP_011526548 XM_011528247 XP_011526549 XM_011528248 XP_011526550 XM_011528249 XP_011526551 XM_011528250 XP_011526552 XM_011528251 XP_011526553 XM_011528252 XP_011526554 NM_003331 NP_003322
Function	Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain. {ECO:0000269|PubMed:7526154}.
Tissue Specificity	Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines. {ECO:0000269|PubMed:2156206}.
Top Pathways	Jak-STAT signaling pathway, Toxoplasmosis, Hepatitis C, Osteoclast differentiation, Measles

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SignalSilence ® Tyk2 siRNA I - 14254 from Cell Signaling Technology Category siRNA Prices $256.00 Sizes 300 µl (3 nmol) Species Reactivities Human

Tyk 2 CRISPR/Cas9 KO Plasmid (h) - sc-400902 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Tyk 2 HDR Plasmid (h) - sc-400902-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Tyk 2 Double Nickase Plasmid (h) - sc-400902-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Tyk 2 Double Nickase Plasmid (h2) - sc-400902-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Tyk 2 CRISPR Activation Plasmid (h) - sc-400902-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Tyk 2 CRISPR Activation Plasmid (h2) - sc-400902-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

Tyk 2 Lentiviral Activation Particles (h) - sc-400902-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Tyk 2 Lentiviral Activation Particles (h2) - sc-400902-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Tyk 2 siRNA (h) - sc-36764 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Tyk 2 shRNA Plasmid (h) - sc-36764-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Tyk 2 shRNA (h) Lentiviral Particles - sc-36764-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Tyk2 RNAi - H00007297-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® siRNA - SIHK2401 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK2400 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK2402 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN2151 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2151 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02249 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr02249

TYK2 siRNA (Human) - CRH4991 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TYK2 - MBS8231426 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human TYK2 (NM_003331.4) - SHH438408 from Creative biogene Category siRNA Species Reactivities Human

Human TYK2 siRNA - orb265493 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

TYK2 shRNA Plasmid (Human) - CHH4991 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

TYK2 miRNA 3'UTR clone - MiUTR3H-01918 from Creative biogene Species Reactivities Human

Search more