TYK2

Gene Symbol	TYK2
Entrez Gene	7297
Alt Symbol	IMD35, JTK1
Species	Human
Gene Type	protein-coding
Description	tyrosine kinase 2
Other Description	non-receptor tyrosine-protein kinase TYK2
Swissprots	Q6QB10 Q96CH0 P29597
Accessions	AAS37680 EAW84099 EAW84100 P29597 AK222672 BAD96392 AK303627 BAG64635 AK308360 AK308379 BC014243 AAH14243 CR995139 DA864169 DQ892692 ABM83618 DQ895955 ABM86881 X54637 CAA38449 XM_011528245 XP_011526547 XM_011528246 XP_011526548 XM_011528247 XP_011526549 XM_011528248 XP_011526550 XM_011528249 XP_011526551 XM_011528250 XP_011526552 XM_011528251 XP_011526553 XM_011528252 XP_011526554 NM_003331 NP_003322
Function	Probably involved in intracellular signal transduction by being involved in the initiation of type I IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain. {ECO:0000269|PubMed:7526154}.
Tissue Specificity	Observed in all cell lines analyzed. Expressed in a variety of lymphoid and non-lymphoid cell lines. {ECO:0000269|PubMed:2156206}.
Top Pathways	Jak-STAT signaling pathway, Toxoplasmosis, Hepatitis C, Osteoclast differentiation, Measles

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human TYK2 protein fragment - ab125539 from Abcam Category Protein Prices $239.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Active human TYK2 protein fragment - ab196057 from Abcam Category Protein Prices $612.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Human TYK2 peptide - ab40717 from Abcam Category Peptide

Human TYK2 protein fragment - ab112369 from Abcam Category Protein Source Wheat germ Species Human

TYK2 Antibody Blocking Peptide - LS-E10559 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TYK2 Antibody Blocking Peptide - LS-E31380 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human Tyk2 Protein - H00007297-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TYK2 - H00007297-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

TYK2 - H00007297-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

TYK2 - P5659 from Acris Antibodies Category Protein Prices $840.00 Sizes 5 µg Species Human

TYK2 Peptide - 7177P from ProSci Category Peptide Species Human

TYK2 fusion protein - Ag9442 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

TYK2 fusion protein - ag9462 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Tyk2 Active Human Recombinant Protein - GWB-35FD7B from Genway Biotech Category Protein Prices $410.00 Sizes 10 µg Species Human

Recombinant Human TYK2 - TYK2-31641TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human TYK2, His-tagged - TYK2-3508H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human TYK2, His-tagged - TYK2-702H from Creative Biomart Category Protein Source Baculovirus-infected Sf9 cell Species Human

Recombinant Human TYK2 - TYK2-345H from Creative Biomart Category Protein Source Mammalian Cells Species Human

Recombinant Human TYK2 (Active), GST-tagged - TYK2-1505H from Creative Biomart Category Protein Source Sf9 Cells Species Human

Recombinant Tyrosine Kinase 2 (Tyk2) - RPB595Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Tyrosine Kinase 2 (Tyk2) - RPB595Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

TYK2 (V1048) Peptide - BS3713P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Tyrosine Kinase 2 (Tyk2) - RPB595Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Non-receptor tyrosine-protein kinase TYK2(TYK2) ,partial - CSB-YP025391HU CSB-EP025391HU CSB-BP025391HU CSB-MP025391HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Tyk 2 (120-255) - sc-4285 WB from Santa Cruz Biotechnology Category Protein Prices $88.00 Sizes 10 µg/0.1 ml Species Human

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