Gene Symbol |
TAF7L
|
Entrez Gene |
54457
|
Alt Symbol |
CT40, TAF2Q
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
|
Other Description |
RNA polymerase II TBP-associated factor subunit Q|TATA box-binding protein-associated factor 50 kDa|TBP-associated factor, RNA polymerase II, Q|cancer/testis antigen 40|transcription initiation factor TFIID 50 kDa subunit|transcription initiation factor TFIID subunit 7-like
|
Swissprots |
Q5H9L4 Q9BXU5 Q5H9L6 Q9H5R0 Q86XI4
|
Accessions |
CCQ43724 EAX02847 EAX02848 EAX02849 EAX02850 EAX02851 EAX02852 Q5H9L4 AF285595 AAK31974 AK026810 BAB15560 AK308261 BC043391 AAH43391 DB042169 DB455298 XM_005262151 XP_005262208 XM_005262152 XP_005262209 XM_006724664 XP_006724727 NM_001168474 NP_001161946 NM_024885 NP_079161
|
Function |
Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis (By similarity). {ECO:0000250}.
|
Subcellular Location |
Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Cytoplasmic in spermatogonia and early spermatocytes (preleptotene, leptotene, and zygotene); translocates into the nuclei of pachytene spermatocytes and round spermatids. {ECO:0000250}.
|
Tissue Specificity |
Testis-specific. {ECO:0000269|PubMed:11279525}.
|
Top Pathways |
Basal transcription factors
|