Gene Symbol | TAF7L |
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Entrez Gene | 54457 |
Alt Symbol | CT40, TAF2Q |
Species | Human |
Gene Type | protein-coding |
Description | TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa |
Other Description | RNA polymerase II TBP-associated factor subunit Q|TATA box-binding protein-associated factor 50 kDa|TBP-associated factor, RNA polymerase II, Q|cancer/testis antigen 40|transcription initiation factor TFIID 50 kDa subunit|transcription initiation factor TFIID subunit 7-like |
Swissprots | Q5H9L4 Q9BXU5 Q5H9L6 Q9H5R0 Q86XI4 |
Accessions | CCQ43724 EAX02847 EAX02848 EAX02849 EAX02850 EAX02851 EAX02852 Q5H9L4 AF285595 AAK31974 AK026810 BAB15560 AK308261 BC043391 AAH43391 DB042169 DB455298 XM_005262151 XP_005262208 XM_005262152 XP_005262209 XM_006724664 XP_006724727 NM_001168474 NP_001161946 NM_024885 NP_079161 |
Function | Probably functions as a spermatogensis-specific component of the DNA-binding general transcription factor complex TFIID, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. May play a role in spermatogenesis (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Cytoplasmic in spermatogonia and early spermatocytes (preleptotene, leptotene, and zygotene); translocates into the nuclei of pachytene spermatocytes and round spermatids. {ECO:0000250}. |
Tissue Specificity | Testis-specific. {ECO:0000269|PubMed:11279525}. |
Top Pathways | Basal transcription factors |
TAF7L CRISPR/Cas9 KO Plasmid (h) - sc-412281 from Santa Cruz Biotechnology
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TAF7L HDR Plasmid (h) - sc-412281-HDR from Santa Cruz Biotechnology
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TAF7L Double Nickase Plasmid (h) - sc-412281-NIC from Santa Cruz Biotechnology
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TAF7L Double Nickase Plasmid (h2) - sc-412281-NIC-2 from Santa Cruz Biotechnology
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TAF7L CRISPR Activation Plasmid (h) - sc-412281-ACT from Santa Cruz Biotechnology
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TAF7L CRISPR Activation Plasmid (h2) - sc-412281-ACT-2 from Santa Cruz Biotechnology
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TAF7L Lentiviral Activation Particles (h) - sc-412281-LAC from Santa Cruz Biotechnology
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TAF7L Lentiviral Activation Particles (h2) - sc-412281-LAC-2 from Santa Cruz Biotechnology
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TAF7L siRNA (h) - sc-90911 from Santa Cruz Biotechnology
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TAF7L shRNA Plasmid (h) - sc-90911-SH from Santa Cruz Biotechnology
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TAF7L shRNA (h) Lentiviral Particles - sc-90911-V from Santa Cruz Biotechnology
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TAF7L RNAi - H00054457-R01 from Novus Biologicals
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MISSION® esiRNA - EHU087891 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN20979 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND20979 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07459 from Sigma-Aldrich
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TAF7L siRNA (Human) - CRJ0066 from Cohesion Biosciences
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TAF7L - MBS8224434 from MyBioSource
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shRNA set against Human TAF7L (NM_024885.3) - SHH422803 from Creative biogene
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Human TAF7L siRNA - orb270567 from Biorbyt
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TAF7L shRNA Plasmid (Human) - CHJ0066 from Cohesion Biosciences
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