Gene Symbol | MMP21 |
---|---|
Entrez Gene | 118856 |
Alt Symbol | MMP-21 |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 21 |
Other Description | matrix metalloproteinase 21|matrix metalloproteinase-21 |
Swissprots | Q8NG02 Q5VZP9 Q8N119 |
Accessions | AAM78033 AAW62254 EAW49230 Q8N119 AF331526 AAM92903 AF520613 AAM75352 BC156368 AAI56369 BC172493 AAI72493 XM_011539257 XP_011537559 NM_147191 NP_671724 |
Function | May have an important and specific function in tumor progression and embryogenesis. Cleaves alpha-1-antitrypsin. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Identified in fetal brain, kidney and liver. In adult tissues found primarily in ovary, kidney, liver, lung, placenta, brain and peripheral blood leukocytes. Expressed as well in various cancer cell lines. {ECO:0000269|PubMed:12490321, ECO:0000269|PubMed:12617721}. |