Gene Symbol | MMP21 |
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Entrez Gene | 118856 |
Alt Symbol | MMP-21 |
Species | Human |
Gene Type | protein-coding |
Description | matrix metallopeptidase 21 |
Other Description | matrix metalloproteinase 21|matrix metalloproteinase-21 |
Swissprots | Q8NG02 Q5VZP9 Q8N119 |
Accessions | AAM78033 AAW62254 EAW49230 Q8N119 AF331526 AAM92903 AF520613 AAM75352 BC156368 AAI56369 BC172493 AAI72493 XM_011539257 XP_011537559 NM_147191 NP_671724 |
Function | May have an important and specific function in tumor progression and embryogenesis. Cleaves alpha-1-antitrypsin. |
Subcellular Location | Secreted {ECO:0000305}. |
Tissue Specificity | Identified in fetal brain, kidney and liver. In adult tissues found primarily in ovary, kidney, liver, lung, placenta, brain and peripheral blood leukocytes. Expressed as well in various cancer cell lines. {ECO:0000269|PubMed:12490321, ECO:0000269|PubMed:12617721}. |
MMP-21 CRISPR/Cas9 KO Plasmid (h) - sc-414131 from Santa Cruz Biotechnology
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MMP-21 HDR Plasmid (h) - sc-414131-HDR from Santa Cruz Biotechnology
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MMP-21 Double Nickase Plasmid (h) - sc-414131-NIC from Santa Cruz Biotechnology
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MMP-21 Double Nickase Plasmid (h2) - sc-414131-NIC-2 from Santa Cruz Biotechnology
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MMP-21 CRISPR Activation Plasmid (h) - sc-414131-ACT from Santa Cruz Biotechnology
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MMP-21 CRISPR Activation Plasmid (h2) - sc-414131-ACT-2 from Santa Cruz Biotechnology
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MMP-21 Lentiviral Activation Particles (h) - sc-414131-LAC from Santa Cruz Biotechnology
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MMP-21 Lentiviral Activation Particles (h2) - sc-414131-LAC-2 from Santa Cruz Biotechnology
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MMP-21 siRNA (h) - sc-62627 from Santa Cruz Biotechnology
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MMP-21 shRNA Plasmid (h) - sc-62627-SH from Santa Cruz Biotechnology
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MMP-21 shRNA (h) Lentiviral Particles - sc-62627-V from Santa Cruz Biotechnology
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MMP21 RNAi - H00118856-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN14430 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14430 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR00663 from Sigma-Aldrich
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MMP21 siRNA (Human) - CRJ4599 from Cohesion Biosciences
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shRNA set against Human Mmp21 (NM_147191.1) - SHH343012 from Creative biogene
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shRNA set against Human MMP21(NM_147191.1) - SHH193763 from Creative biogene
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Human MMP21 siRNA - orb275100 from Biorbyt
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MMP21 shRNA Plasmid (Human) - CHJ4599 from Cohesion Biosciences
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MMP21 miRNA 3'UTR clone - MiUTR1H-06353 from Creative biogene
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