CRTAM

Gene Symbol CRTAM
Entrez Gene 56253
Alt Symbol CD355
Species Human
Gene Type protein-coding
Description cytotoxic and regulatory T cell molecule
Other Description class I MHC restricted T cell associated molecule|class-I MHC-restricted T cell associated molecule|class-I MHC-restricted T-cell-associated molecule|cytotoxic and regulatory T-cell molecule
Swissprots Q6IRX2 O95727 Q59EI1
Accessions CCF77045 EAW67532 O95727 AB209830 BAD93067 AF001622 AAC80267 AK293470 BAG56963 AK313578 BAG36349 BC070266 AAH70266 BX118379 CA309993 CK004240 DC305734 HQ447587 ADQ32073 XM_011542900 XP_011541202 NM_001304782 NP_001291711 NM_019604 NP_062550
Function Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo. {ECO:0000250|UniProtKB:Q149L7, ECO:0000269|PubMed:15811952}.
Subcellular Location Membrane {ECO:0000255}; Single-pass type I membrane protein {ECO:0000255}.
Tissue Specificity In the immune system, expression is restricted to activated class-I MHC-restricted cells, including NKT and CD8 cells. Strongly expressed in spleen, thymus, small intestine, peripheral blood leukocyte, and in Purkinje neurons in cerebellum. Expressed at much lower levels in testis, ovary, colon, lung and lymphoid tissues. {ECO:0000269|PubMed:10811014, ECO:0000269|PubMed:15811952, ECO:0000269|PubMed:16300832}.

CRTAM CRISPR/Cas9 KO Plasmid (h) - sc-412694 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRTAM HDR Plasmid (h) - sc-412694-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRTAM Double Nickase Plasmid (h) - sc-412694-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRTAM Double Nickase Plasmid (h2) - sc-412694-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRTAM CRISPR Activation Plasmid (h) - sc-412694-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRTAM CRISPR Activation Plasmid (h2) - sc-412694-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRTAM Lentiviral Activation Particles (h) - sc-412694-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRTAM Lentiviral Activation Particles (h2) - sc-412694-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CRTAM siRNA (h) - sc-60451 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRTAM shRNA Plasmid (h) - sc-60451-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CRTAM shRNA (h) Lentiviral Particles - sc-60451-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU004901 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN6595 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6595 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08700 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08700

CRTAM siRNA (Human) - CRJ1116 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRTAM - MBS8212539 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CRTAM (NM_019604.2) - SHH269797 from Creative biogene

Category siRNA
Species Reactivities Human

Human CRTAM siRNA - orb271617 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CRTAM shRNA Plasmid (Human) - CHJ1116 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CRTAM miRNA 3'UTR clone - MiUTR1H-02441 from Creative biogene

Species Reactivities Human
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